List of EC numbers (EC 3)
This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
EC 3.1: Acting on Ester Bonds
EC 3.1.1: Carboxylic Ester Hydrolases
- EC 3.1.1.1: carboxylesterase
- EC 3.1.1.2: arylesterase
- EC 3.1.1.3: triacylglycerol lipase
- EC 3.1.1.4: phospholipase A2
- EC 3.1.1.5: lysophospholipase
- EC 3.1.1.6: acetylesterase
- EC 3.1.1.7: acetylcholinesterase
- EC 3.1.1.8: cholinesterase
- EC 3.1.1.9: deleted
- EC 3.1.1.10: tropinesterase
- EC 3.1.1.11: pectinesterase
- EC 3.1.1.12: deleted
- EC 3.1.1.13: sterol esterase
- EC 3.1.1.14: chlorophyllase
- EC 3.1.1.15: L-arabinonolactonase
- EC 3.1.1.16: deleted, mixture of EC 5.3.3.4 and EC 3.1.1.24
- EC 3.1.1.17: gluconolactonase
- EC 3.1.1.18: deleted, included in EC 3.1.1.17
- EC 3.1.1.19: uronolactonase
- EC 3.1.1.20: tannase
- EC 3.1.1.21: deleted, see EC 3.1.1.1 and EC 3.1.1.3
- EC 3.1.1.22: hydroxybutyrate-dimer hydrolase
- EC 3.1.1.23: acylglycerol lipase
- EC 3.1.1.24: 3-oxoadipate enol-lactonase
- EC 3.1.1.25: 1,4-lactonase
- EC 3.1.1.26: galactolipase
- EC 3.1.1.27: 4-pyridoxolactonase
- EC 3.1.1.28: acylcarnitine hydrolase
- EC 3.1.1.29: aminoacyl-tRNA hydrolase
- EC 3.1.1.30: D-arabinonolactonase
- EC 3.1.1.31: 6-phosphogluconolactonase
- EC 3.1.1.32: phospholipase A1
- EC 3.1.1.33: 6-acetylglucose deacetylase
- EC 3.1.1.34: lipoprotein lipase
- EC 3.1.1.35: dihydrocoumarin hydrolase
- EC 3.1.1.36: limonin-D-ring-lactonase
- EC 3.1.1.37: steroid-lactonase
- EC 3.1.1.38: triacetate-lactonase
- EC 3.1.1.39: actinomycin lactonase
- EC 3.1.1.40: orsellinate-depside hydrolase
- EC 3.1.1.41: cephalosporin-C deacetylase
- EC 3.1.1.42: chlorogenate hydrolase
- EC 3.1.1.43: alpha-amino-acid esterase
- EC 3.1.1.44: 4-methyloxaloacetate esterase
- EC 3.1.1.45: carboxymethylenebutenolidase
- EC 3.1.1.46: deoxylimonate A-ring-lactonase
- EC 3.1.1.47: 1-alkyl-2-acetylglycerophosphocholine esterase
- EC 3.1.1.48: fusarinine-C ornithinesterase
- EC 3.1.1.49: sinapine esterase
- EC 3.1.1.50: wax-ester hydrolase
- EC 3.1.1.51: phorbol-diester hydrolase
- EC 3.1.1.52: phosphatidylinositol deacylase
- EC 3.1.1.53: sialate O-acetylesterase
- EC 3.1.1.54: acetoxybutynylbithiophene deacetylase
- EC 3.1.1.55: acetylsalicylate deacetylase
- EC 3.1.1.56: methylumbelliferyl-acetate deacetylase
- EC 3.1.1.57: 2-pyrone-4,6-dicarboxylate lactonase
- EC 3.1.1.58: N-acetylgalactosaminoglycan deacetylase
- EC 3.1.1.59: juvenile-hormone esterase
- EC 3.1.1.60: bis(2-ethylhexyl)phthalate esterase
- EC 3.1.1.61: protein-glutamate methylesterase
- EC 3.1.1.62: now EC 3.5.1.47
- EC 3.1.1.63: 11-cis-retinyl-palmitate hydrolase
- EC 3.1.1.64: all-trans-retinyl-palmitate hydrolase
- EC 3.1.1.65: L-rhamnono-1,4-lactonase
- EC 3.1.1.66: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
- EC 3.1.1.67: fatty-acyl-ethyl-ester synthase
- EC 3.1.1.68: xylono-1,4-lactonase
- EC 3.1.1.69: now EC 3.5.1.89
- EC 3.1.1.70: cetraxate benzylesterase
- EC 3.1.1.71: acetylalkylglycerol acetylhydrolase
- EC 3.1.1.72: acetylxylan esterase
- EC 3.1.1.73: feruloyl esterase
- EC 3.1.1.74: cutinase
- EC 3.1.1.75: poly(3-hydroxybutyrate) depolymerase
- EC 3.1.1.76: poly(3-hydroxyoctanoate) depolymerase
- EC 3.1.1.77: acyloxyacyl hydrolase
- EC 3.1.1.78: polyneuridine-aldehyde esterase
- EC 3.1.1.79: hormone-sensitive lipase
- EC 3.1.1.80: acetylajmaline esterase
- EC 3.1.1.81: quorum-quenching N-acyl-homoserine lactonase
- EC 3.1.1.82: pheophorbidase
- EC 3.1.1.83: monoterpene epsilon-lactone hydrolase
- EC 3.1.1.84: cocaine esterase
- EC 3.1.1.85: pimelyl-(acyl-carrier protein) methyl ester esterase
- EC 3.1.1.86: rhamnogalacturonan acetylesterase
- EC 3.1.1.87: fumonisin B1 esterase
- EC 3.1.1.88: pyrethroid hydrolase
- EC 3.1.1.89: protein phosphatase methylesterase-1
- EC 3.1.1.90: all-trans-retinyl ester 13-cis isomerohydrolase
- EC 3.1.1.91: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase
- EC 3.1.1.92: 4-sulfomuconolactone hydrolase
- EC 3.1.1.93: mycophenolic acid acyl-glucuronide esterase
EC 3.1.2: Thioester Hydrolases
- EC 3.1.2.1: acetyl-CoA hydrolase
- EC 3.1.2.2: palmitoyl-CoA hydrolase
- EC 3.1.2.3: succinyl-CoA hydrolase
- EC 3.1.2.4: 3-hydroxyisobutyryl-CoA hydrolase
- EC 3.1.2.5: hydroxymethylglutaryl-CoA hydrolase
- EC 3.1.2.6: hydroxyacylglutathione hydrolase
- EC 3.1.2.7: glutathione thiolesterase
- EC 3.1.2.10: formyl-CoA hydrolase
- EC 3.1.2.11: acetoacetyl-CoA hydrolase
- EC 3.1.2.12: S-formylglutathione hydrolase
- EC 3.1.2.13: S-succinylglutathione hydrolase
- EC 3.1.2.14: oleoyl-(acyl-carrier-protein) hydrolase
- EC 3.1.2.15: ubiquitin thiolesterase
- EC 3.1.2.16: citrate lyase deacetylase
- EC 3.1.2.17: (S)-methylmalonyl-CoA hydrolase
- EC 3.1.2.18: ADP-dependent short-chain-acyl-CoA hydrolase
- EC 3.1.2.19: ADP-dependent medium-chain-acyl-CoA hydrolase
- EC 3.1.2.20: acyl-CoA hydrolase
- EC 3.1.2.21: Dodecanoyl-(acyl-carrier-protein) hydrolase
- EC 3.1.2.22: palmitoyl(protein) hydrolase
- EC 3.1.2.23: 4-hydroxybenzoyl-CoA thioesterase
- EC 3.1.2.24: transferred entry now EC 3.13.1.3
- EC 3.1.2.25: phenylacetyl-CoA hydrolase
- EC 3.1.2.26: bile-acid-CoA hydrolase
- EC 3.1.2.27: choloyl-CoA hydrolase
- EC 3.1.2.28: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase
- EC 3.1.2.29: fluoroacetyl-CoA thioesterase
EC 3.1.3: Phosphoric Monoester Hydrolases
- EC 3.1.3.1: alkaline phosphatase
- EC 3.1.3.2: acid phosphatase
- EC 3.1.3.3: phosphoserine phosphatase
- EC 3.1.3.4: phosphatidate phosphatase
- EC 3.1.3.5: 5'-nucleotidase
- EC 3.1.3.6: 3'-nucleotidase
- EC 3.1.3.7: 3'(2'),5'-bisphosphate nucleotidase
- EC 3.1.3.8: 3-phytase
- EC 3.1.3.9: glucose-6-phosphatase
- EC 3.1.3.10: glucose-1-phosphatase
- EC 3.1.3.11: fructose-bisphosphatase
- EC 3.1.3.12: trehalose-phosphatase
- EC 3.1.3.13: bisphosphoglycerate phosphatase
- EC 3.1.3.14: methylphosphothioglycerate phosphatase
- EC 3.1.3.15: histidinol-phosphatase
- EC 3.1.3.16: protein serine/threonine phosphatase
- EC 3.1.3.17: (phosphorylase) phosphatase
- EC 3.1.3.18: phosphoglycolate phosphatase
- EC 3.1.3.19: glycerol-2-phosphatase
- EC 3.1.3.20: phosphoglycerate phosphatase
- EC 3.1.3.21: glycerol-1-phosphatase
- EC 3.1.3.22: mannitol-1-phosphatase
- EC 3.1.3.23: sugar-phosphatase
- EC 3.1.3.24: sucrose-phosphatase
- EC 3.1.3.25: inositol-phosphate phosphatase
- EC 3.1.3.26: 4-phytase
- EC 3.1.3.27: phosphatidylglycerophosphatase
- EC 3.1.3.28: ADP-phosphoglycerate phosphatase
- EC 3.1.3.29: N-acylneuraminate-9-phosphatase
- EC 3.1.3.30: deleted, included in EC 3.1.3.31
- EC 3.1.3.31: nucleotidase
- EC 3.1.3.32: polynucleotide 3'-phosphatase
- EC 3.1.3.33: polynucleotide 5'-phosphatase
- EC 3.1.3.34: deoxynucleotide 3'-phosphatase
- EC 3.1.3.35: thymidylate 5'-phosphatase
- EC 3.1.3.36: phosphoinositide 5-phosphatase
- EC 3.1.3.37: sedoheptulose-bisphosphatase
- EC 3.1.3.38: 3-phosphoglycerate phosphatase
- EC 3.1.3.39: streptomycin-6-phosphatase
- EC 3.1.3.40: guanidinodeoxy-scyllo-inositol-4-phosphatase
- EC 3.1.3.41: 4-nitrophenylphosphatase
- EC 3.1.3.42: (glycogen-synthase-D) phosphatase
- EC 3.1.3.43: (pyruvate dehydrogenase (acetyl-transferring))-phosphatase
- EC 3.1.3.44: (acetyl-CoA carboxylase)-phosphatase
- EC 3.1.3.45: 3-deoxy-manno-octulosonate-8-phosphatase
- EC 3.1.3.46: fructose-2,6-bisphosphate 2-phosphatase
- EC 3.1.3.47: (hydroxymethylglutaryl-CoA reductase (NADPH))-phosphatase
- EC 3.1.3.48: protein-tyrosine-phosphatase
- EC 3.1.3.49: (pyruvate kinase)-phosphatase
- EC 3.1.3.50: sorbitol-6-phosphatase
- EC 3.1.3.51: dolichyl-phosphatase
- EC 3.1.3.52: (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase
- EC 3.1.3.53: (myosin-light-chain) phosphatase
- EC 3.1.3.54: fructose-2,6-bisphosphate 6-phosphatase
- EC 3.1.3.55: caldesmon-phosphatase
- EC 3.1.3.56: inositol-polyphosphate 5-phosphatase
- EC 3.1.3.57: inositol-1,4-bisphosphate 1-phosphatase
- EC 3.1.3.58: sugar-terminal-phosphatase
- EC 3.1.3.59: alkylacetylglycerophosphatase
- EC 3.1.3.60: phosphoenolpyruvate phosphatase
- EC 3.1.3.61: deleted
- EC 3.1.3.62: multiple inositol-polyphosphate phosphatase
- EC 3.1.3.63: 2-carboxy-D-arabinitol-1-phosphatase
- EC 3.1.3.64: phosphatidylinositol-3-phosphatase
- EC 3.1.3.65: now with EC 3.1.3.64
- EC 3.1.3.66: phosphatidylinositol-3,4-bisphosphate 4-phosphatase
- EC 3.1.3.67: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
- EC 3.1.3.68: 2-deoxyglucose-6-phosphatase
- EC 3.1.3.69: glucosylglycerol 3-phosphatase
- EC 3.1.3.70: mannosyl-3-phosphoglycerate phosphatase
- EC 3.1.3.71: 2-phosphosulfolactate phosphatase
- EC 3.1.3.72: 5-phytase
- EC 3.1.3.73: a-ribazole phosphatase
- EC 3.1.3.74: pyridoxal phosphatase
- EC 3.1.3.75: phosphoethanolamine/phosphocholine phosphatase
- EC 3.1.3.76: lipid-phosphate phosphatase
- EC 3.1.3.77: acireductone synthase
- EC 3.1.3.78: phosphatidylinositol-4,5-bisphosphate 4-phosphatase
- EC 3.1.3.79: mannosylfructose-phosphate phosphatase
- EC 3.1.3.80: 2,3-bisphosphoglycerate 3-phosphatase
- EC 3.1.3.81: diacylglycerol diphosphate phosphatase
- EC 3.1.3.82: D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
- EC 3.1.3.83: D-glycero-alpha-D-manno-heptose 1,7-bisphosphate 7-phosphatase
- EC 3.1.3.84: ADP-ribose 1''-phosphate phosphatase
- EC 3.1.3.85: glucosyl-3-phosphoglycerate phosphatase
- EC 3.1.3.86: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
- EC 3.1.3.87: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
- EC 3.1.3.88: 5''-phosphoribostamycin phosphatase
EC 3.1.4: Phosphoric Diester Hydrolases
- EC 3.1.4.1: phosphodiesterase I
- EC 3.1.4.2: glycerophosphocholine phosphodiesterase
- EC 3.1.4.3: lecithinase C
- EC 3.1.4.4: phospholipase D
- EC 3.1.4.5: now EC 3.1.21.1
- EC 3.1.4.6: now EC 3.1.22.1
- EC 3.1.4.7: now EC 3.1.31.1
- EC 3.1.4.8: now EC 3.1.27.3
- EC 3.1.4.9: now EC 3.1.30.2
- EC 3.1.4.10: now EC 4.6.1.13
- EC 3.1.4.11: phosphoinositide phospholipase C
- EC 3.1.4.12: sphingomyelin phosphodiesterase
- EC 3.1.4.13: serine-ethanolaminephosphate phosphodiesterase
- EC 3.1.4.14: (acyl-carrier-protein) phosphodiesterase
- EC 3.1.4.15: adenylyl-(glutamate—ammonia ligase) hydrolase
- EC 3.1.4.16: 2',3'-cyclic-nucleotide 2'-phosphodiesterase
- EC 3.1.4.17: 3',5'-cyclic-nucleotide phosphodiesterase
- EC 3.1.4.18: now EC 3.1.16.1
- EC 3.1.4.19: now EC 3.1.13.3
- EC 3.1.4.20: now EC 3.1.13.1
- EC 3.1.4.21: now EC 3.1.30.1
- EC 3.1.4.22: now EC 3.1.27.5
- EC 3.1.4.23: now EC 3.1.27.1
- EC 3.1.4.24: deleted
- EC 3.1.4.25: now EC 3.1.11.1
- EC 3.1.4.26: deleted
- EC 3.1.4.27: now EC 3.1.11.2
- EC 3.1.4.28: now EC 3.1.11.3
- EC 3.1.4.29: deleted
- EC 3.1.4.30: now EC 3.1.21.2
- EC 3.1.4.31: now EC 3.1.11.4
- EC 3.1.4.32: deleted
- EC 3.1.4.33: deleted
- EC 3.1.4.34: deleted
- EC 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase
- EC 3.1.4.36: now with EC 3.1.4.43
- EC 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase
- EC 3.1.4.38: glycerophosphocholine cholinephosphodiesterase
- EC 3.1.4.39: alkylglycerophosphoethanolamine phosphodiesterase
- EC 3.1.4.40: CMP-N-acylneuraminate phosphodiesterase
- EC 3.1.4.41: sphingomyelin phosphodiesterase D
- EC 3.1.4.42: glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
- EC 3.1.4.43: glycerophosphoinositol inositolphosphodiesterase
- EC 3.1.4.44: glycerophosphoinositol glycerophosphodiesterase
- EC 3.1.4.45: N-acetylglucosamine-1-phosphodiester a-N-acetylglucosaminidase
- EC 3.1.4.46: glycerophosphodiester phosphodiesterase
- EC 3.1.4.47: now EC 4.6.1.14
- EC 3.1.4.48: dolichylphosphate-glucose phosphodiesterase
- EC 3.1.4.49: dolichylphosphate-mannose phosphodiesterase
- EC 3.1.4.50: glycosylphosphatidylinositol phospholipase D
- EC 3.1.4.51: glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
- EC 3.1.4.52: cyclic-guanylate-specific phosphodiesterase
- EC 3.1.4.53: 3',5'-cyclic-AMP phosphodiesterase
- EC 3.1.4.54: N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
EC 3.1.6: Sulfuric Ester Hydrolases
- EC 3.1.6.1: arylsulfatase
- EC 3.1.6.2: steryl-sulfatase
- EC 3.1.6.3: glycosulfatase
- EC 3.1.6.4: N-acetylgalactosamine-6-sulfatase
- EC 3.1.6.5: deleted
- EC 3.1.6.6: choline-sulfatase
- EC 3.1.6.7: cellulose-polysulfatase
- EC 3.1.6.8: cerebroside-sulfatase
- EC 3.1.6.9: chondro-4-sulfatase
- EC 3.1.6.10: chondro-6-sulfatase
- EC 3.1.6.11: disulfoglucosamine-6-sulfatase
- EC 3.1.6.12: N-acetylgalactosamine-4-sulfatase
- EC 3.1.6.13: iduronate-2-sulfatase
- EC 3.1.6.14: N-acetylglucosamine-6-sulfatase
- EC 3.1.6.15: N-sulfoglucosamine-3-sulfatase
- EC 3.1.6.16: monomethyl-sulfatase
- EC 3.1.6.17: D-lactate-2-sulfatase
- EC 3.1.6.18: glucuronate-2-sulfatase
EC 3.1.7: Diphosphoric Monoester Hydrolases
- EC 3.1.7.1: prenyl-diphosphatase
- EC 3.1.7.2: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
- EC 3.1.7.3: monoterpenyl-diphosphatase
- EC 3.1.7.4: sclareol cyclase
- EC 3.1.7.5: geranylgeranyl diphosphate diphosphatase
- EC 3.1.7.6: farnesyl diphosphatase
- EC 3.1.7.7: drimenol cyclase
- EC 3.1.7.8: tuberculosinol synthase
- EC 3.1.7.9: isotuberculosinol synthase
- EC 3.1.7.10: (13E)-labda-7,13-dien-15-ol synthase
- EC 3.1.7.11: geranyl diphosphate diphosphatase
EC 3.1.8: Phosphoric Triester Hydrolases
EC 3.1.11: Exodeoxyribonucleases Producing 5'-Phosphomonoesters
- EC 3.1.11.1: exodeoxyribonuclease I
- EC 3.1.11.2: exodeoxyribonuclease III
- EC 3.1.11.3: exodeoxyribonuclease (lambda-induced)
- EC 3.1.11.4: exodeoxyribonuclease (phage SP3-induced)
- EC 3.1.11.5: exodeoxyribonuclease V
- EC 3.1.11.6: exodeoxyribonuclease VII
EC 3.1.13: Exoribonucleases Producing 5'-Phosphomonoesters
- EC 3.1.13.1: exoribonuclease II
- EC 3.1.13.2: exoribonuclease H
- EC 3.1.13.3: oligonucleotidase
- EC 3.1.13.4: poly(A)-specific ribonuclease
- EC 3.1.13.5: ribonuclease D
EC 3.1.14: Exoribonucleases Producing 3'-Phosphomonoesters
EC 3.1.15: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters
EC 3.1.16: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters
EC 3.1.21: Endodeoxyribonucleases Producing 5'-Phosphomonoesters
- EC 3.1.21.1: deoxyribonuclease I
- EC 3.1.21.2: deoxyribonuclease IV (phage-T4-induced)
- EC 3.1.21.3: type I site-specific deoxyribonuclease
- EC 3.1.21.4: type II site-specific deoxyribonuclease
- EC 3.1.21.5: type III site-specific deoxyribonuclease
- EC 3.1.21.6: CC-preferring endodeoxyribonuclease
- EC 3.1.21.7: deoxyribonuclease V
EC 3.1.22: Endodeoxyribonucleases Producing 3'-Phosphomonoesters
EC 3.1.23: and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5
EC 3.1.25: Site-Specific Endodeoxyribonucleases Specific for Altered Bases
- EC 3.1.25.1: deoxyribonuclease (pyrimidine dimer)
- EC 3.1.25.2: now EC 4.2.99.18
EC 3.1.26: Endoribonucleases Producing 5'-Phosphomonoesters
- EC 3.1.26.1: Physarum polycephalum ribonuclease
- EC 3.1.26.2: ribonuclease alpha
- EC 3.1.26.3: ribonuclease III
- EC 3.1.26.4: calf thymus ribonuclease H
- EC 3.1.26.5: ribonuclease P
- EC 3.1.26.6: ribonuclease IV
- EC 3.1.26.7: ribonuclease P4
- EC 3.1.26.8: ribonuclease M5
- EC 3.1.26.9: ribonuclease (poly-(U)-specific)
- EC 3.1.26.10: ribonuclease IX
- EC 3.1.26.11: ribonuclease Z
- EC 3.1.26.12: ribonuclease E
- EC 3.1.26.13: retroviral ribonuclease H
- EC 3.1.26.n1: now EC 3.1.26.12
EC 3.1.27: Endoribonucleases Producing 3'-Phosphomonoesters
- EC 3.1.27.1: ribonuclease T2
- EC 3.1.27.2: Bacillus subtilis ribonuclease
- EC 3.1.27.3: ribonuclease T1
- EC 3.1.27.4: ribonuclease U2
- EC 3.1.27.5: pancreatic ribonuclease
- EC 3.1.27.6: Enterobacter ribonuclease
- EC 3.1.27.7: ribonuclease F
- EC 3.1.27.8: ribonuclease V
- EC 3.1.27.9: tRNA-intron endonuclease
- EC 3.1.27.10: rRNA endonuclease
EC 3.1.30: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters
- EC 3.1.30.1: Aspergillus nuclease S1
- EC 3.1.30.2: Serratia marcescens nuclease
EC 3.1.31: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters
EC 3.2: Glycosylases
EC 3.2.1: Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
- EC 3.2.1.1: α-amylase
- EC 3.2.1.2: β-amylase
- EC 3.2.1.3: glucan 1,4-a-glucosidase
- EC 3.2.1.4: cellulase
- EC 3.2.1.5: deleted
- EC 3.2.1.6: endo-1,3(4)-b-glucanase
- EC 3.2.1.7: inulinase
- EC 3.2.1.8: endo-1,4-β-xylanase
- EC 3.2.1.9: deleted
- EC 3.2.1.10: oligo-1,6-glucosidase
- EC 3.2.1.11: dextranase
- EC 3.2.1.12: deleted, included in EC 3.2.1.54
- EC 3.2.1.13: deleted, included in EC 3.2.1.54
- EC 3.2.1.14: chitinase
- EC 3.2.1.15: polygalacturonase
- EC 3.2.1.16: deleted
- EC 3.2.1.17: lysozyme
- EC 3.2.1.18: exo-a-sialidase
- EC 3.2.1.19: deleted
- EC 3.2.1.20: a-glucosidase
- EC 3.2.1.21: b-glucosidase
- EC 3.2.1.22: α-galactosidase
- EC 3.2.1.23: b-galactosidase
- EC 3.2.1.24: a-mannosidase
- EC 3.2.1.25: b-mannosidase
- EC 3.2.1.26: b-fructofuranosidase
- EC 3.2.1.27: deleted
- EC 3.2.1.28: α,α-trehalase
- EC 3.2.1.29: deleted, included in EC 3.2.1.52
- EC 3.2.1.30: deleted, included in EC 3.2.1.52
- EC 3.2.1.31: β-glucuronidase
- EC 3.2.1.32: xylan endo-1,3-b-xylosidase
- EC 3.2.1.33: amylo-1,6-glucosidase
- EC 3.2.1.34: deleted, included in EC 3.2.1.35
- EC 3.2.1.35: hyaluronoglucosaminidase
- EC 3.2.1.36: hyaluronoglucuronidase
- EC 3.2.1.37: xylan 1,4-b-xylosidase
- EC 3.2.1.38: b-D-fucosidase
- EC 3.2.1.39: glucan endo-1,3-b-D-glucosidase
- EC 3.2.1.40: a-L-rhamnosidase
- EC 3.2.1.41: pullulanase
- EC 3.2.1.42: GDP-glucosidase
- EC 3.2.1.43: b-L-rhamnosidase
- EC 3.2.1.44: fucoidanase
- EC 3.2.1.45: glucosylceramidase
- EC 3.2.1.46: galactosylceramidase
- EC 3.2.1.47: galactosylgalactosylglucosylceramidase
- EC 3.2.1.48: Sucrose alpha-glucosidase
- EC 3.2.1.49: a-N-acetylgalactosaminidase
- EC 3.2.1.50: α-N-acetylglucosaminidase
- EC 3.2.1.51: a-L-fucosidase
- EC 3.2.1.52: b-L-N-acetylhexosaminidase
- EC 3.2.1.53: b-N-acetylgalactosaminidase
- EC 3.2.1.54: cyclomaltodextrinase
- EC 3.2.1.55: a-N-arabinofuranosidase
- EC 3.2.1.56: glucuronosyl-disulfoglucosamine glucuronidase
- EC 3.2.1.57: isopullulanase
- EC 3.2.1.58: glucan 1,3-b-glucosidase
- EC 3.2.1.59: glucan endo-1,3-a-glucosidase
- EC 3.2.1.60: glucan 1,4-a-maltotetraohydrolase
- EC 3.2.1.61: mycodextranase
- EC 3.2.1.62: glycosylceramidase
- EC 3.2.1.63: 1,2-alpha-L-fucosidase
- EC 3.2.1.64: 2,6-b-fructan 6-levanbiohydrolase
- EC 3.2.1.65: levanase
- EC 3.2.1.66: quercitrinase
- EC 3.2.1.67: galacturan 1,4-a-galacturonidase
- EC 3.2.1.68: isoamylase
- EC 3.2.1.69: deleted, included in EC 3.2.1.41
- EC 3.2.1.70: glucan 1,6-a-glucosidase
- EC 3.2.1.71: glucan endo-1,2-b-glucosidase
- EC 3.2.1.72: xylan 1,3-b-xylosidase
- EC 3.2.1.73: licheninase
- EC 3.2.1.74: glucan 1,4-b-glucosidase
- EC 3.2.1.75: glucan endo-1,6-b-glucosidase
- EC 3.2.1.76: L-iduronidase
- EC 3.2.1.77: mannan 1,2-(1,3)-a-mannosidase
- EC 3.2.1.78: mannan endo-1,4-b-mannosidase
- EC 3.2.1.79: deleted, included in EC 3.2.1.55
- EC 3.2.1.80: fructan b-fructosidase
- EC 3.2.1.81: agarase
- EC 3.2.1.82: exo-poly-a-galacturonosidase
- EC 3.2.1.83: k-carrageenase
- EC 3.2.1.84: glucan 1,3-a-glucosidase
- EC 3.2.1.85: 6-phospho-b-galactosidase
- EC 3.2.1.86: 6-phospho-b-glucosidase
- EC 3.2.1.87: capsular-polysaccharide endo-1,3-a-galactosidase
- EC 3.2.1.88: b-L-arabinosidase
- EC 3.2.1.89: arabinogalactan endo-1,4-b-galactosidase
- EC 3.2.1.90: Deleted, not sufficiently characterised.
- EC 3.2.1.91: cellulose 1,4-b-cellobiosidase
- EC 3.2.1.92: peptidoglycan b-N-acetylmuramidase
- EC 3.2.1.93: a,a-phosphotrehalase
- EC 3.2.1.94: glucan 1,6-a-isomaltosidase
- EC 3.2.1.95: dextran 1,6-a-isomaltotriosidase
- EC 3.2.1.96: mannosyl-glycoprotein endo-b-N-acetylglucosaminidase
- EC 3.2.1.97: glycopeptide a-N-acetylgalactosaminidase
- EC 3.2.1.98: glucan 1,4-a-maltohexaosidase
- EC 3.2.1.99: arabinan endo-1,5-a-L-arabinosidase
- EC 3.2.1.100: mannan 1,4-mannobiosidase
- EC 3.2.1.101: mannan endo-1,6-a-mannosidase
- EC 3.2.1.102: blood-group-substance endo-1,4-b-galactosidase
- EC 3.2.1.103: keratan-sulfate endo-1,4-b-galactosidase
- EC 3.2.1.104: steryl-b-glucosidase
- EC 3.2.1.105: strictosidine b-glucosidase
- EC 3.2.1.106: mannosyl-oligosaccharide glucosidase
- EC 3.2.1.107: protein-glucosylgalactosylhydroxylysine glucosidase
- EC 3.2.1.108: lactase
- EC 3.2.1.109: endogalactosaminidase
- EC 3.2.1.110: mucinaminylserine mucinaminidase
- EC 3.2.1.111: 1,3-alpha-L-fucosidase
- EC 3.2.1.112: 2-deoxyglucosidase
- EC 3.2.1.113: mannosyl-oligosaccharide 1,2-a-mannosidase
- EC 3.2.1.114: mannosyl-oligosaccharide 1,3-1,6-a-mannosidase
- EC 3.2.1.115: branched-dextran exo-1,2-a-glucosidase
- EC 3.2.1.116: glucan 1,4-a-maltotriohydrolase
- EC 3.2.1.117: amygdalin b-glucosidase
- EC 3.2.1.118: prunasin b-glucosidase
- EC 3.2.1.119: vicianin b-glucosidase
- EC 3.2.1.120: oligoxyloglucan b-glycosidase
- EC 3.2.1.121: polymannuronate hydrolase
- EC 3.2.1.122: maltose-6'-phosphate glucosidase
- EC 3.2.1.123: endoglycosylceramidase
- EC 3.2.1.124: 3-deoxy-2-octulosonidase
- EC 3.2.1.125: raucaffricine b-glucosidase
- EC 3.2.1.126: coniferin b-glucosidase
- EC 3.2.1.127: 1,6-alpha-L-fucosidase
- EC 3.2.1.128: glycyrrhizinate beta-glucuronidase
- EC 3.2.1.129: endo-a-sialidase
- EC 3.2.1.130: glycoprotein endo-a-1,2-mannosidase
- EC 3.2.1.131: xylan a-1,2-glucuronosidase
- EC 3.2.1.132: chitosanase
- EC 3.2.1.133: glucan 1,4-a-maltohydrolase
- EC 3.2.1.134: difructose-anhydride synthase
- EC 3.2.1.135: neopullulanase
- EC 3.2.1.136: glucuronoarabinoxylan endo-1,4-b-xylanase
- EC 3.2.1.137: mannan exo-1,2-1,6-a-mannosidase
- EC 3.2.1.138: now EC 4.2.2.15
- EC 3.2.1.139: Alpha-glucuronidase
- EC 3.2.1.140: lacto-N-biosidase
- EC 3.2.1.141: 4-a-D-((1-4)-a-D-glucano)trehalose trehalohydrolase
- EC 3.2.1.142: limit dextrinase
- EC 3.2.1.143: poly(ADP-ribose) glycohydrolase
- EC 3.2.1.144: 3-deoxyoctulosonase
- EC 3.2.1.145: galactan 1,3-b-galactosidase
- EC 3.2.1.146: b-galactofuranosidase
- EC 3.2.1.147: thioglucosidase
- EC 3.2.1.148: now EC 4.4.1.21
- EC 3.2.1.149: b-primeverosidase
- EC 3.2.1.150: oligoxyloglucan reducing-end-specific cellobiohydrolase
- EC 3.2.1.151: xyloglucan-specific endo-b-1,4-glucanase
- EC 3.2.1.152: mannosylglycoprotein endo-b-mannosidase
- EC 3.2.1.153: fructan b-(2,1)-fructosidase
- EC 3.2.1.154: fructan b-(2,6)-fructosidase
- EC 3.2.1.155: xyloglucan-specific exo-beta-1,4-glucanase
- EC 3.2.1.156: oligosaccharide reducing-end xylanase
- EC 3.2.1.157: iota-carrageenase
- EC 3.2.1.158: alpha-agarase
- EC 3.2.1.159: alpha-neoagaro-oligosaccharide hydrolase
- EC 3.2.1.160: now EC 3.2.1.155
- EC 3.2.1.161: beta-apiosyl-beta-glucosidase
- EC 3.2.1.162: lambda-carrageenase
- EC 3.2.1.163: 1,6-alpha-D-mannosidase
- EC 3.2.1.164: galactan endo-1,6-beta-galactosidase
- EC 3.2.1.165: exo-1,4-beta-D-glucosaminidase
- EC 3.2.1.166: blood group B branched chain alpha-1,3-galactosidase
- EC 3.2.1.167: blood group B linear chain alpha-1,3-galactosidase
- EC 3.2.1.168: hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase
- EC 3.2.1.169: protein O-GlcNAcase
- EC 3.2.1.170: mannosylglycerate hydrolase
- EC 3.2.1.171: rhamnogalacturonan hydrolase
- EC 3.2.1.172: unsaturated rhamnogalacturonyl hydrolase
- EC 3.2.1.173: rhamnogalacturonan galacturonohydrolase
- EC 3.2.1.174: rhamnogalacturonan rhamnohydrolase
- EC 3.2.1.175: beta-D-glucopyranosyl abscisate beta-glucosidase
- EC 3.2.1.176: cellulose 1,4-beta-cellobiosidase (reducing end)
- EC 3.2.1.177: alpha-D-xyloside xylohydrolase
- EC 3.2.1.178: beta-porphyranase
- EC 3.2.1.179: gellan tetrasaccharide unsaturated glucuronyl hydrolase
- EC 3.2.1.180: unsaturated chondroitin disaccharide hydrolase
- EC 3.2.1.181: galactan endo-beta-1,3-galactanase
- EC 3.2.1.182: 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase
- EC 3.2.1.183: UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
- EC 3.2.1.184: UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)
EC 3.2.2: Hydrolysing N-Glycosyl Compounds
- EC 3.2.2.1: purine nucleosidase
- EC 3.2.2.2: inosine nucleosidase
- EC 3.2.2.3: uridine nucleosidase
- EC 3.2.2.4: AMP nucleosidase
- EC 3.2.2.5: NAD+ nucleosidase
- EC 3.2.2.6: NAD(P)+ nucleosidase
- EC 3.2.2.7: adenosine nucleosidase
- EC 3.2.2.8: ribosylpyrimidine nucleosidase
- EC 3.2.2.9: adenosylhomocysteine nucleosidase
- EC 3.2.2.10: pyrimidine-5'-nucleotide nucleosidase
- EC 3.2.2.11: b-aspartyl-N-acetylglucosaminidase
- EC 3.2.2.12: inosinate nucleosidase
- EC 3.2.2.13: 1-methyladenosine nucleosidase
- EC 3.2.2.14: NMN nucleosidase
- EC 3.2.2.15: DNA-deoxyinosine glycosylase
- EC 3.2.2.16: methylthioadenosine nucleosidase
- EC 3.2.2.17: deoxyribodipyrimidine endonucleosidase
- EC 3.2.2.18: deleted, included in EC 3.5.1.52
- EC 3.2.2.19: ADP-ribosylarginine hydrolase
- EC 3.2.2.20: DNA-3-methyladenine glycosylase I
- EC 3.2.2.21: DNA-3-methyladenine glycosylase II
- EC 3.2.2.22: rRNA N-glycosylase
- EC 3.2.2.23: DNA-formamidopyrimidine glycosylase
- EC 3.2.2.24: ADP-ribosyl-(dinitrogen reductase) hydrolase
- EC 3.2.2.25: N-methyl nucleosidase
- EC 3.2.2.26: futalosine hydrolase
- EC 3.2.2.27: uracil-DNA glycosylase
- EC 3.2.2.28: double-stranded uracil-DNA glycosylase
- EC 3.2.2.29: thymine-DNA glycosylase
EC 3.3: Acting on Ether Bonds
EC 3.3.1: Thioether and trialkylsulfonium hydrolases
- EC 3.3.1.1: adenosylhomocysteinase
- EC 3.3.1.2: adenosylmethionine hydrolase
- EC 3.3.1.3: now EC 3.2.1.148
EC 3.3.2: Ether Hydrolases
- EC 3.3.2.1: isochorismatase
- EC 3.3.2.2: alkenylglycerophosphocholine hydrolase
- EC 3.3.2.3: epoxide hydrolase
- EC 3.3.2.4: trans-epoxysuccinate hydrolase
- EC 3.3.2.5: alkenylglycerophosphoethanolamine hydrolase
- EC 3.3.2.6: leukotriene-A4 hydrolase
- EC 3.3.2.7: hepoxilin-epoxide hydrolase
- EC 3.3.2.8: limonene-1,2-epoxide hydrolase
- EC 3.3.2.9: microsomal epoxide hydrolase
- EC 3.3.2.10: soluble epoxide hydrolase
- EC 3.3.2.11: cholesterol-5,6-oxide hydrolase
EC 3.4: act on peptide bonds – Peptidase
EC 3.4.1 α-amino acyl peptide hydrolases (discontinued)
EC 3.4.2 Peptidyl amino acid hydrolases (discontinued)
EC 3.4.3 Dipeptide Hydrolases (discontinued)
- EC 3.4.3.1: glycyl-glycine dipeptidase, now EC 3.4.13.18
- EC 3.4.3.2: glycyl-leucine dipeptidase, now EC 3.4.13.18
- EC 3.4.3.3: aminoacyl-histidine dipeptidase, carnosinase, now EC 3.4.13.3
- EC 3.4.3.4: aminoacyl-methylhistidine dipeptidase, anserinase, now EC 3.4.13.5
- EC 3.4.3.5: cysteinyl-glycine dipeptidase, now EC 3.4.13.6
- EC 3.4.3.6: iminodipeptidase, now EC 3.4.13.8
- EC 3.4.3.7: imidodipeptidase, prolidase, now EC 3.4.13.9
EC 3.4.4 Peptidyl Peptide Hydrolases (discontinued)
- EC 3.4.4.1: pepsin, now EC 3.4.23.1
- EC 3.4.4.2: pepsin B, now EC 3.4.23.2
- EC 3.4.4.3: rennin, now EC 3.4.23.4
- EC 3.4.4.4: trypsin, now EC 3.4.21.4
- EC 3.4.4.5: chymotrypsin, now EC 3.4.21.1
- EC 3.4.4.6: chymotrypsin B, now EC 3.4.21.1
- EC 3.4.4.7: pancreatopeptidase E, now EC 3.4.21.36 and EC 3.4.21.37
- EC 3.4.4.8: enteropeptidase, now EC 3.4.21.9
- EC 3.4.4.9: cathepsin C, now EC 3.4.14.1
- EC 3.4.4.10: papain now EC 3.4.22.2
- EC 3.4.4.11: chymopapain, now EC 3.4.22.6
- EC 3.4.4.12: ficin, now EC 3.4.22.3
- EC 3.4.4.13: thrombin, now EC 3.4.21.5
- EC 3.4.4.14: plasmin, now EC 3.4.21.7
- EC 3.4.4.15: renin, now EC 3.4.23.15
- EC 3.4.4.16: subtilopeptidase A, now EC 3.4.21.62 to EC 3.4.21.67
- EC 3.4.4.17: aspergillopeptidase A, now EC 3.4.23.20 to EC 3.4.23.30 3.4.23.30
- EC 3.4.4.18: streptococcus peptidase A, now EC 3.4.22.10
- EC 3.4.4.19: clostridiopeptidase A, now EC 3.4.24.3
- EC 3.4.4.20: clostridiopeptidase B, now EC 3.4.22.8
- EC 3.4.4.21: kallikrein, now EC 3.4.21.34
- EC 3.4.4.22: recommended Name never specified, now EC 3.4.23.3
- EC 3.4.4.23: recommended Name never specified, now EC 3.4.23.5
- EC 3.4.4.24: recommended Name never specified, now EC 3.4.22.32 and EC 3.4.22.33
- EC 3.4.4.25: keratinase deleted
EC 3.4.11 Aminopeptidases
- EC 3.4.11.1: leucyl aminopeptidase
- EC 3.4.11.2: membrane alanyl aminopeptidase
- EC 3.4.11.3: cystinyl aminopeptidase
- EC 3.4.11.4: tripeptide aminopeptidase
- EC 3.4.11.5: prolyl aminopeptidase
- EC 3.4.11.6: aminopeptidase B
- EC 3.4.11.7: glutamyl aminopeptidase
- EC 3.4.11.8: Transferred entry: pyroglutamyl aminopeptidase. Now EC 3.4.19.3, pyroglutamyl-peptidase I
- EC 3.4.11.9: X-Pro aminopeptidase
- EC 3.4.11.10: bacterial leucyl aminopeptidase
- EC 3.4.11.11: Deleted entry: aminopeptidase
- EC 3.4.11.12: Deleted entry: thermophilic aminopeptidase
- EC 3.4.11.13: Clostridial aminopeptidase
- EC 3.4.11.14: cytosol alanyl aminopeptidase
- EC 3.4.11.15: aminopeptidase Y
- EC 3.4.11.16: X-Trp aminopeptidase
- EC 3.4.11.17: tryptophanyl aminopeptidase
- EC 3.4.11.18: methionyl aminopeptidase
- EC 3.4.11.19: D-stereospecific aminopeptidase
- EC 3.4.11.20: aminopeptidase Ey
- EC 3.4.11.21: aspartyl aminopeptidase
- EC 3.4.11.22: aminopeptidase I
- EC 3.4.11.23: PepB aminopeptidase
- EC 3.4.11.24: aminopeptidase S
- EC 3.4.11.25: beta-peptidyl aminopeptidase
- EC 3.4.11.26: intermediate cleaving peptidase 55
EC 3.4.13 Dipeptidases
- EC 3.4.13.1: glycyl-glycine dipeptidase, now EC 3.4.13.18
- EC 3.4.13.2: glycyl-leucine dipeptidase, now EC 3.4.13.18
- EC 3.4.13.3: X-His dipeptidase
- EC 3.4.13.4: X-Arg dipeptidase
- EC 3.4.13.5: X-methyl-His dipeptidase
- EC 3.4.13.6: Transferred entry: Cys-Gly dipeptidase. Now EC 3.4.11.2, membrane alanyl aminopeptidase
- EC 3.4.13.7: Glu-Glu dipeptidase
- EC 3.4.13.8: Transferred entry: Pro-X dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase
- EC 3.4.13.9: X-Pro dipeptidase
- EC 3.4.13.10: Transferred entry: β-aspartyldipeptidase. Now EC 3.4.19.5, β-aspartyl-peptidase
- EC 3.4.13.11: Transferred entry: dipeptidase. Now EC 3.4.13.19, membrane dipeptidase
- EC 3.4.13.12: Met-X dipeptidase
- EC 3.4.13.13: Transferred entry: homocarnosinase. Now EC 3.4.13.3, X-His dipeptidase
- EC 3.4.13.14: Deleted entry: γ-glutamyldipeptidase
- EC 3.4.13.15: Transferred entry: N2-β-alanylarginine dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase
- EC 3.4.13.16: Deleted entry: aspartylphenylalanine dipeptidase
- EC 3.4.13.17: non-stereospecific dipeptidase
- EC 3.4.13.18: cytosol nonspecific dipeptidase
- EC 3.4.13.19: membrane dipeptidase
- EC 3.4.13.20: beta-Ala-His dipeptidase
- EC 3.4.13.21: dipeptidase E
- EC 3.4.13.22: D-Ala-D-Ala dipeptidase
EC 3.4.14 Dipeptidyl peptidases and tripeptidyl peptidases
- EC 3.4.14.1: dipeptidyl-peptidase I
- EC 3.4.14.2: dipeptidyl-peptidase II
- EC 3.4.14.3: Transferred entry: acylamino-acid-releasing enzyme. Now EC 3.4.19.1, acylaminoacyl-peptidase
- EC 3.4.14.4: dipeptidyl-peptidase III
- EC 3.4.14.5: dipeptidyl-peptidase IV
- EC 3.4.14.6: dipeptidyl-dipeptidase
- EC 3.4.14.7: Deleted entry: tetralysine endopeptidase
- EC 3.4.14.8: Transferred entry: tripeptidyl peptidase. Now EC 3.4.14.10, tripeptidyl-peptidase II
- EC 3.4.14.9: tripeptidyl-peptidase I
- EC 3.4.14.10: tripeptidyl-peptidase II
- EC 3.4.14.11: Xaa-Pro dipeptidyl-peptidase
- EC 3.4.14.12: Xaa-Xaa-Pro tripeptidyl-peptidase
EC 3.4.15 Peptidyl dipeptidases
- EC 3.4.15.1: peptidyl-dipeptidase A
- EC 3.4.15.2: Transferred entry: pepdidyl carboxyamidase. Now EC 3.4.19.2, peptidyl-glycinamidase
- EC 3.4.15.3: Transferred entry: dipeptidyl carboxypeptidase. Now EC 3.4.15.5, peptidyl-dipeptidase Dcp
- EC 3.4.15.4: Peptidyl-dipeptidase B
- EC 3.4.15.5: Peptidyl-dipeptidase Dcp
- EC 3.4.15.6: cyanophycinase
EC 3.4.16 Serine type carboxypeptidases
- EC 3.4.16.1: Transferred entry: serine carboxypeptidase. Now EC 3.4.16.6, carboxypeptidase D
- EC 3.4.16.2: lysosomal Pro-X carboxypeptidase
- EC 3.4.16.3: Transferred entry: tyrosine carboxypeptidase. Now included with EC 3.4.16.5, carboxypeptidase C
- EC 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase
- EC 3.4.16.5: carboxypeptidase c
- EC 3.4.16.6: carboxypeptidase D
EC 3.4.17 Metallocarboxypeptidases
- EC 3.4.17.1: carboxypeptidase A
- EC 3.4.17.2: carboxypeptidase B
- EC 3.4.17.3: lysine carboxypeptidase
- EC 3.4.17.4: Gly-X carboxypeptidase
- EC 3.4.17.5: Deleted entry: aspartate carboxypeptidase
- EC 3.4.17.6: alanine carboxypeptidase
- EC 3.4.17.7: Transferred entry: acylmuramoyl-alanine carboxypeptidase. Now EC 3.5.1.28, N-acetylmuramoyl-L-alanine amidase
- EC 3.4.17.8: muramoylpentapeptide carboxypeptidase
- EC 3.4.17.9: Transferred entry: carboxypeptidase S. Now included with EC 3.4.17.4, Gly-Xaa carboxypeptidase
- EC 3.4.17.10: carboxypeptidase E
- EC 3.4.17.11: glutamate carboxypeptidase
- EC 3.4.17.12: carboxypeptidase M
- EC 3.4.17.13: Muramoyltetrapeptide carboxypeptidase
- EC 3.4.17.14: Zinc D-Ala-D-Ala carboxypeptidase
- EC 3.4.17.15: carboxypeptidase A2
- EC 3.4.17.16: Membrane Pro-X carboxypeptidase
- EC 3.4.17.17: tubulinyl-Tyr carboxypeptidase
- EC 3.4.17.18: carboxypeptidase T
- EC 3.4.17.19: Carboxypeptidase Taq
- EC 3.4.17.20: Carboxypeptidase u
- EC 3.4.17.21: Glutamate carboxypeptidase II
- EC 3.4.17.22: Metallocarboxypeptidase D
- EC 3.4.17.23: angiotensin-converting enzyme 2
EC 3.4.18 Cysteine type carboxypeptidases
EC 3.4.19 Omega peptidases
- EC 3.4.19.1: acylaminoacyl-peptidase
- EC 3.4.19.2: peptidyl-glycinamidase
- EC 3.4.19.3: pyroglutamyl-peptidase I
- EC 3.4.19.4: Deleted entry: N-acetylmethionylpeptide peptidase
- EC 3.4.19.5: beta-aspartyl-peptidase
- EC 3.4.19.6: pyroglutamyl-peptidase II
- EC 3.4.19.7: N-Formylmethionyl-peptidase
- EC 3.4.19.8: Transferred entry: now EC 3.4.17.21, glutamate carboxypeptidase II
- EC 3.4.19.9: gamma-glutamyl hydrolase
- EC 3.4.19.10: Transferred entry: acylmuramoyl-Ala peptidase. Now EC 3.5.1.28, N-acetylmuramoyl-L-alanine amidase
- EC 3.4.19.11: gamma-D-Glutamyl-meso-diaminopimelate peptidase
- EC 3.4.19.12: ubiquitinyl hydrolase 1
- EC 3.4.19.13: glutathione hydrolase
- EC 3.4.19.14: leukotriene-C4 hydrolase
EC 3.4.21: Serine proteases
- EC 3.4.21.1: chymotrypsin
- EC 3.4.21.2: chymotrypsin C
- EC 3.4.21.3: metridin
- EC 3.4.21.4: trypsin
- EC 3.4.21.5: thrombin
- EC 3.4.21.6: coagulation factor Xa
- EC 3.4.21.7: plasmin
- EC 3.4.21.8: Transferred entry: kallikrein. Now EC 3.4.21.34 (plasma kallikrein) and EC 3.4.21.35 (tissue kallikrein)
- EC 3.4.21.9: enteropeptidase
- EC 3.4.21.10: acrosin
- EC 3.4.21.11: Transferred entry: elastase. Now EC 3.4.21.37, leukocyte elastase
- EC 3.4.21.12: alpha-lytic endopeptidase
- EC 3.4.21.13: Transferred entry: Phaseolus proteinase. Now EC 3.4.16.6, carboxypeptidase D
- EC 3.4.21.14: Transferred entry: now EC 3.4.21.67 endopeptidase So
- EC 3.4.21.15: Transferred entry: Aspergillus alkaline proteinase. Now EC 3.4.21.63, oryzin
- EC 3.4.21.16: Deleted entry: Alternaria serine proteinase
- EC 3.4.21.17: Deleted entry: Arthrobacter serine proteinase
- EC 3.4.21.18: Deleted entry: Tenebrio α-proteinase
- EC 3.4.21.19: glutamyl endopeptidase
- EC 3.4.21.20: cathepsin G
- EC 3.4.21.21: coagulation factor VIIa
- EC 3.4.21.22: coagulation factor IXa
- EC 3.4.21.23: Deleted entry: Vipera russelli proteinase
- EC 3.4.21.24: Deleted entry: red cell neutral endopeptidase
- EC 3.4.21.25: cucumisin
- EC 3.4.21.26: prolyl oligopeptidase
- EC 3.4.21.27: coagulation factor XIa
- EC 3.4.21.28: Transferred entry: Agkistrodon serine proteinase. Now EC 3.4.21.74, venombin A
- EC 3.4.21.29: Transferred entry: Bothrops atrox serine proteinase. Now EC 3.4.21.74, venombin A
- EC 3.4.21.30: Transferred entry: Crotalus adamanteus serine proteinase. Now EC 3.4.21.74, venombin A
- EC 3.4.21.31: Transferred entry: urokinase. Now EC 3.4.21.73, u-plasminogen activator
- EC 3.4.21.32: brachyurin
- EC 3.4.21.33: Deleted entry: Entomophthora collagenolytic proteinase
- EC 3.4.21.34: plasma kallikrein
- EC 3.4.21.35: renal tissue kallikrein
- EC 3.4.21.36: pancreatic elastase
- EC 3.4.21.37: leukocyte elastase
- EC 3.4.21.38: coagulation factor XIIa
- EC 3.4.21.39: chymase
- EC 3.4.21.40: Deleted entry: submandibular proteinase A
- EC 3.4.21.41: complement subcomponent C1r
- EC 3.4.21.42: complement subcomponent C1s
- EC 3.4.21.43: classical-complement-pathway C3/C5 convertase
- EC 3.4.21.44: Transferred entry: complement component C5 convertase. Now EC 3.4.21.43, classical-complement-pathway C3/C5 convertase
- EC 3.4.21.45: complement factor I
- EC 3.4.21.46: complement factor D
- EC 3.4.21.47: alternative-complement-pathway C3/C5 convertase
- EC 3.4.21.48: cerevisin
- EC 3.4.21.49: hypodermin C
- EC 3.4.21.50: lysyl endopeptidase
- EC 3.4.21.51: Deleted entry: Leukocyte-membrane neutral endopeptidase
- EC 3.4.21.52: Deleted entry: Cathepsin R
- EC 3.4.21.53: Endopeptidase La
- EC 3.4.21.54: gamma-Renin
- EC 3.4.21.55: Venombin AB
- EC 3.4.21.56: Deleted entry: euphorbain. Now considered EC 3.4.21.25, cucumisin
- EC 3.4.21.57: Leucyl endopeptidase
- EC 3.4.21.58: Deleted entry: prohormone serine proteinase
- EC 3.4.21.59: Tryptase
- EC 3.4.21.60: Scutelarin
- EC 3.4.21.61: Kexin
- EC 3.4.21.62: Subtilisin
- EC 3.4.21.63: Oryzin
- EC 3.4.21.64: Endopeptidase K
- EC 3.4.21.65: Thermomycolin
- EC 3.4.21.66: Thermitase
- EC 3.4.21.67: Endopeptidase So
- EC 3.4.21.68: t-Plasminogen activator
- EC 3.4.21.69: Protein C (activated)
- EC 3.4.21.70: Pancreatic endopeptidase E
- EC 3.4.21.71: Pancreatic elastase II
- EC 3.4.21.72: IgA-specific serine endopeptidase
- EC 3.4.21.73: u-Plasminogen activator
- EC 3.4.21.74: Venombin A
- EC 3.4.21.75: Furin
- EC 3.4.21.76: Myeloblastin
- EC 3.4.21.77: semenogelase
- EC 3.4.21.78: Granzyme A
- EC 3.4.21.79: Granzyme B
- EC 3.4.21.80: Streptogrisin A
- EC 3.4.21.81: Streptogrisin B
- EC 3.4.21.82: Glutamyl endopeptidase II
- EC 3.4.21.83: Oligopeptidase B
- EC 3.4.21.84: Limulus clotting factor C
- EC 3.4.21.85: Limulus clotting factor B
- EC 3.4.21.86: Limulus clotting enzyme
- EC 3.4.21.87: Transferred entry: omptin. Now EC 3.4.23.49, omptin. The enzyme is not a serine protease, as thought previously, but an aspartate protease
- EC 3.4.21.88: Repressor LexA
- EC 3.4.21.89: Signal peptidase I
- EC 3.4.21.90: Togavirin
- EC 3.4.21.91: Flavivirin
- EC 3.4.21.92: Endopeptidase Clp
- EC 3.4.21.93: Proprotein convertase 1
- EC 3.4.21.94: Proprotein convertase 2
- EC 3.4.21.95: Snake venom factor V activator
- EC 3.4.21.96: Lactocepin
- EC 3.4.21.97: assemblin
- EC 3.4.21.98: hepacivirin
- EC 3.4.21.99: spermosin
- EC 3.4.21.100: pseudomonalisin
- EC 3.4.21.101: xanthomonalisin
- EC 3.4.21.102: C-terminal processing peptidase
- EC 3.4.21.103: physarolisin
- EC 3.4.21.104: mannan-binding lectin-associated serine protease-2
- EC 3.4.21.105: rhomboid protease
- EC 3.4.21.106: hepsin
- EC 3.4.21.107: peptidase Do
- EC 3.4.21.108: HtrA2 peptidase
- EC 3.4.21.109: matriptase
- EC 3.4.21.110: C5a peptidase
- EC 3.4.21.111: aqualysin 1
- EC 3.4.21.112: site-1 protease
- EC 3.4.21.113: pestivirus NS3 polyprotein peptidase
- EC 3.4.21.114: equine arterivirus serine peptidase
- EC 3.4.21.115: infectious pancreatic necrosis birnavirus Vp4 peptidase
- EC 3.4.21.116: SpoIVB peptidase
- EC 3.4.21.117: stratum corneum chymotryptic enzyme
- EC 3.4.21.118: kallikrein 8
- EC 3.4.21.119: kallikrein 13
- EC 3.4.21.120: oviductin
EC 3.4.22 Cysteine proteases
- EC 3.4.22.1: cathepsin B
- EC 3.4.22.2: papain
- EC 3.4.22.3: ficain
- EC 3.4.22.4: bromelain (stem). Now EC 3.4.22.32 (stem bromelain) and EC 3.4.22.33 (fruit bromelain)
- EC 3.4.22.5: bromelain (juice). Now EC 3.4.22.32 (stem bromelain) and EC 3.4.22.33 (fruit bromelain)
- EC 3.4.22.6: chymopapain
- EC 3.4.22.7: asclepain
- EC 3.4.22.8: clostripain
- EC 3.4.22.9: yeast proteinase B. Now EC 3.4.21.48, cerevisin
- EC 3.4.22.10: streptopain
- EC 3.4.22.11: insulinase. Now EC 3.4.24.56, insulysin
- EC 3.4.22.12: gamma-glutamyl hydrolase. Now EC 3.4.19.9, γ-glutamyl hydrolase
- EC 3.4.22.13: Deleted entry: staphylococcal cysteine proteinase
- EC 3.4.22.14: actinidain
- EC 3.4.22.15: cathepsin L
- EC 3.4.22.16: cathepsin H
- EC 3.4.22.17: Transferred entry: calpain. Now EC 3.4.22.53, calpain-2
- EC 3.4.22.18: Transferred entry: prolyl endopeptidase (thiol-dependent). Now EC 3.4.21.26, prolyl oligopeptidase
- EC 3.4.22.19: Transferred entry: endo-oligopeptidase. Now EC 3.4.24.15, thimet oligopeptidase
- EC 3.4.22.20: Deleted entry: dinorphin-converting enzyme
- EC 3.4.22.21: Transferred entry: yeast cysteine proteinase E. Now EC 3.4.25.1, proteasome endopeptidase complex
- EC 3.4.22.22: Transferred entry: yeast cysteine proteinase D. Now EC 3.4.24.37, saccharolysin
- EC 3.4.22.23: Transferred entry: yeast cysteine proteinase F. Now EC 3.4.21.61, kexin
- EC 3.4.22.24: Cathepsin T
- EC 3.4.22.25: Glycyl endopeptidase
- EC 3.4.22.26: Cancer procoagulant
- EC 3.4.22.27: cathepsin S
- EC 3.4.22.28: picornain 3C
- EC 3.4.22.29: picornain 2A
- EC 3.4.22.30: Caricain
- EC 3.4.22.31: Ananain
- EC 3.4.22.32: Stem bromelain
- EC 3.4.22.33: Fruit bromelain
- EC 3.4.22.34: Legumain
- EC 3.4.22.35: Histolysain
- EC 3.4.22.36: caspase-1
- EC 3.4.22.37: Gingipain R
- EC 3.4.22.38: Cathepsin K
- EC 3.4.22.39: adenain
- EC 3.4.22.40: bleomycin hydrolase
- EC 3.4.22.41: cathepsin F
- EC 3.4.22.42: cathepsin O
- EC 3.4.22.43: cathepsin V
- EC 3.4.22.44: nuclear-inclusion-a endopeptidase
- EC 3.4.22.45: helper-component proteinase
- EC 3.4.22.46: L-peptidase
- EC 3.4.22.47: gingipain K
- EC 3.4.22.48: staphopain
- EC 3.4.22.49: separase
- EC 3.4.22.50: V-cath endopeptidase
- EC 3.4.22.51: cruzipain
- EC 3.4.22.52: calpain-1
- EC 3.4.22.53: calpain-2
- EC 3.4.22.54: calpain-3
- EC 3.4.22.55: caspase-2
- EC 3.4.22.56: caspase-3
- EC 3.4.22.57: caspase-4
- EC 3.4.22.58: caspase-5
- EC 3.4.22.59: caspase-6
- EC 3.4.22.60: caspase-7
- EC 3.4.22.61: caspase-8
- EC 3.4.22.62: caspase-9
- EC 3.4.22.63: caspase-10
- EC 3.4.22.64: caspase-11
- EC 3.4.22.65: peptidase 1 (mite)
- EC 3.4.22.66: calicivirin
- EC 3.4.22.67: zingipain
- EC 3.4.22.68: Ulp1 peptidase
- EC 3.4.22.69: SARS coronavirus main proteinase
- EC 3.4.22.70: sortase A
- EC 3.4.22.71: sortase B
EC 3.4.23 Aspartic endopeptidases
- EC 3.4.23.1: pepsin A
- EC 3.4.23.2: pepsin B
- EC 3.4.23.3: gastricsin
- EC 3.4.23.4: chymosin
- EC 3.4.23.5: cathepsin D
- EC 3.4.23.6: now EC 3.4.23.30 pycnoporopepsin
- EC 3.4.23.7: Penicillium janthinellum acid proteinase. Now EC 3.4.23.20, penicillopepsin
- EC 3.4.23.8: yeast proteinase A. Now EC 3.4.23.25, saccharopepsin
- EC 3.4.23.9: Rhizopus acid proteinase. Now EC 3.4.23.21, rhizopuspepsin
- EC 3.4.23.10: Endothia acid proteinase. Now EC 3.4.23.22, endothiapepsin
- EC 3.4.23.11: Deleted entry: thyroid aspartic proteinase
- EC 3.4.23.12: nepenthesin
- EC 3.4.23.13: Deleted entry: Lotus aspartic proteinase
- EC 3.4.23.14: Deleted entry: sorghum aspartic proteinase
- EC 3.4.23.15: renin
- EC 3.4.23.16: HIV-1 retropepsin
- EC 3.4.23.17: Pro-opiomelanocortin converting enzyme
- EC 3.4.23.18: Aspergillopepsin I
- EC 3.4.23.19: Aspergillopepsin II
- EC 3.4.23.20: Penicillopepsin
- EC 3.4.23.21: Rhizopuspepsin
- EC 3.4.23.22: Endothiapepsin
- EC 3.4.23.23: Mucorpepsin
- EC 3.4.23.24: Candidapepsin
- EC 3.4.23.25: Saccharopepsin
- EC 3.4.23.26: Rhodotorulapepsin
- EC 3.4.23.27: physaropepsin. Now EC 3.4.21.103, physarolisin
- EC 3.4.23.28: Acrocylindropepsin
- EC 3.4.23.29: Polyporopepsin
- EC 3.4.23.30: Pycnoporopepsin
- EC 3.4.23.31: Scytalidopepsin A
- EC 3.4.23.32: Scytalidopepsin B
- EC 3.4.23.33: xanthomonapepsin. Now EC 3.4.21.101, xanthomonalisin
- EC 3.4.23.34: Cathepsin e
- EC 3.4.23.35: Barrierpepsin
- EC 3.4.23.36: Signal peptidase II
- EC 3.4.23.37: pseudomonapepsin. Now EC 3.4.21.100, pseudomonalisin
- EC 3.4.23.38: plasmepsin I
- EC 3.4.23.39: plasmepsin II
- EC 3.4.23.40: Phytepsin
- EC 3.4.23.41: yapsin 1
- EC 3.4.23.42: thermopsin
- EC 3.4.23.43: prepilin peptidase
- EC 3.4.23.44: nodavirus endopeptidase
- EC 3.4.23.45: memapsin 1
- EC 3.4.23.46: memapsin 2
- EC 3.4.23.47: HIV-2 retropepsin
- EC 3.4.23.48: plasminogen activator Pla
- EC 3.4.23.49: omptin
- EC 3.4.23.50: human endogenous retrovirus K endopeptidase
- EC 3.4.23.51: HycI peptidase
- EC 3.4.23.52: preflagellin peptidase
EC 3.4.24: Metallopeptidases
- EC 3.4.24.1: atrolysin A
- EC 3.4.24.2: Deleted entry: Sepia proteinase
- EC 3.4.24.3: microbial collagenase
- EC 3.4.24.4: now EC 3.4.24.40 serralysin
- EC 3.4.24.5: Deleted entry: lens neutral proteinase. Now included with EC 3.4.22.53 (calpain-2) and EC 3.4.25.1 (proteasome endopeptidase complex)
- EC 3.4.24.6: leucolysin
- EC 3.4.24.7: interstitial collagenase
- EC 3.4.24.8: Transferred entry: Achromobacter iophagus collagenase. Now EC 3.4.24.3, microbial collagenase
- EC 3.4.24.9: Deleted entry: Trichophyton schoenleinii collagenase
- EC 3.4.24.10: Deleted entry: Trichophyton mentagrophytes keratinase
- EC 3.4.24.11: neprilysin
- EC 3.4.24.12: envelysin
- EC 3.4.24.13: IgA-specific metalloendopeptidase
- EC 3.4.24.14: procollagen N-endopeptidase
- EC 3.4.24.15: thimet oligopeptidase
- EC 3.4.24.16: neurolysin
- EC 3.4.24.17: stromelysin 1
- EC 3.4.24.18: meprin A
- EC 3.4.24.19: procollagen C-endopeptidase
- EC 3.4.24.20: peptidyl-Lys metalloendopeptidase
- EC 3.4.24.21: astacin
- EC 3.4.24.22: stromelysin 2
- EC 3.4.24.23: matrilysin
- EC 3.4.24.24: gelatinase a
- EC 3.4.24.25: vibriolysin
- EC 3.4.24.26: pseudolysin
- EC 3.4.24.27: thermolysin
- EC 3.4.24.28: bacillolysin
- EC 3.4.24.29: aureolysin
- EC 3.4.24.30: coccolysin
- EC 3.4.24.31: mycolysin
- EC 3.4.24.32: beta-Lytic metalloendopeptidase
- EC 3.4.24.33: peptidyl-Asp metalloendopeptidase
- EC 3.4.24.34: neutrophil collagenase
- EC 3.4.24.35: gelatinase B
- EC 3.4.24.36: leishmanolysin
- EC 3.4.24.37: saccharolysin
- EC 3.4.24.38: gametolysin
- EC 3.4.24.39: deuterolysin
- EC 3.4.24.40: serralysin
- EC 3.4.24.41: atrolysin B
- EC 3.4.24.42: atrolysin C
- EC 3.4.24.43: atroxase
- EC 3.4.24.44: atrolysin E
- EC 3.4.24.45: atrolysin F
- EC 3.4.24.46: adamalysin
- EC 3.4.24.47: horrilysin
- EC 3.4.24.48: ruberlysin
- EC 3.4.24.49: bothropasin
- EC 3.4.24.50: bothrolysin
- EC 3.4.24.51: ophiolysin
- EC 3.4.24.52: trimerelysin I
- EC 3.4.24.53: trimerelysin II
- EC 3.4.24.54: mucrolysin
- EC 3.4.24.55: pitrilysin
- EC 3.4.24.56: insulysin
- EC 3.4.24.57: O-sialoglycoprotein endopeptidase
- EC 3.4.24.58: russellysin
- EC 3.4.24.59: mitochondrial intermediate peptidase
- EC 3.4.24.60: dactylysin
- EC 3.4.24.61: nardilysin
- EC 3.4.24.62: magnolysin
- EC 3.4.24.63: meprin B
- EC 3.4.24.64: mitochondrial processing peptidase
- EC 3.4.24.65: macrophage elastase
- EC 3.4.24.66: choriolysin L
- EC 3.4.24.67: choriolysin H
- EC 3.4.24.68: tentoxilysin
- EC 3.4.24.69: bontoxilysin
- EC 3.4.24.70: oligopeptidase A
- EC 3.4.24.71: endothelin-converting enzyme 1
- EC 3.4.24.72: fibrolase
- EC 3.4.24.73: jararhagin
- EC 3.4.24.74: fragilysin
- EC 3.4.24.75: lysostaphin
- EC 3.4.24.76: flavastacin
- EC 3.4.24.77: snapalysin
- EC 3.4.24.78: gpr endopeptidase
- EC 3.4.24.79: pappalysin-1
- EC 3.4.24.80: membrane-type matrix metalloproteinase-1
- EC 3.4.24.81: ADAM10 endopeptidase
- EC 3.4.24.82: ADAMTS-4 endopeptidase
- EC 3.4.24.83: anthrax lethal factor endopeptidase
- EC 3.4.24.84: Ste24 endopeptidase
- EC 3.4.24.85: S2P endopeptidase
- EC 3.4.24.86: ADAM 17 endopeptidase
- EC 3.4.24.87: ADAMTS13 endopeptidase
EC 3.4.25 Threonine endopeptidases
- EC 3.4.25.1: proteasome endopeptidase complex
- EC 3.4.25.2: HslU—HslV peptidase
EC 3.4.99 Endopeptidases of unknown catalytic mechanism
- EC 3.4.99.1: acrocylindricum proteinase. Now EC 3.4.23.28, acrocylindropepsin
- EC 3.4.99.2: Deleted entry: agavain
- EC 3.4.99.3: Deleted entry: angiotensinase
- EC 3.4.99.4: Transferred entry: aspartylendopeptidase. Now EC 3.4.23.12, nepenthesin
- EC 3.4.99.5: Transferred entry: Clostridium histolyticum collagenase 2. Now EC 3.4.24.3, microbial collagenase
- EC 3.4.99.6: Transferred entry: crayfish low-molecular-weight proteinase. Now EC 3.4.24.21, astacin
- EC 3.4.99.7: Deleted entry: euphorbain
- EC 3.4.99.8: Deleted entry: Gliocladium proteinase
- EC 3.4.99.9: Deleted entry: hurain. Now considered EC 3.4.21.25, cucumisin
- EC 3.4.99.10: Transferred entry: insulinase. Now EC 3.4.24.56, insulysin
- EC 3.4.99.11: Deleted entry: Streptomyces alkalophilic keratinase
- EC 3.4.99.12: Deleted entry: Trichophyton mentagrophytes keratinase
- EC 3.4.99.13: Transferred entry: β-lytic proteinase (Mycobacterium sorangium). Now EC 3.4.24.32, β-lytic metalloendopeptidase
- EC 3.4.99.14: Deleted entry: mexicanain
- EC 3.4.99.15: Deleted entry: Paecilomyces proteinase
- EC 3.4.99.16: Deleted entry: Penicillium notatum extracellular proteinase
- EC 3.4.99.17: Deleted entry: peptidoglycan endopeptidase
- EC 3.4.99.18: Deleted entry: pinguinain
- EC 3.4.99.19: Transferred entry: renin. Now EC 3.4.23.15, renin
- EC 3.4.99.20: Deleted entry: scopulariopsis proteinase
- EC 3.4.99.21: Deleted entry: solanain. Now considered EC 3.4.21.25, cucumisin
- EC 3.4.99.22: Transferred entry: staphylokinase. Now EC 3.4.24.29, aureolysin
- EC 3.4.99.23: Deleted entry: tabernamontanain. Now considered EC 3.4.21.25, cucumisin
- EC 3.4.99.24: Deleted entry: Tenebrio α-proteinase
- EC 3.4.99.25: Transferred entry: trametes acid proteinase. Now EC 3.4.23.21, rhizopuspepsin
- EC 3.4.99.26: Transferred entry: urokinase. Now EC 3.4.21.68, t-plasminogen activator
- EC 3.4.99.27: Deleted entry: Echis carinatus prothrombin-activating proteinase
- EC 3.4.99.28: Transferred entry: Oxyuranus scutellatus prothrombin-activating proteinase. Now EC 3.4.21.60, scutelarin
- EC 3.4.99.29: Deleted entry: Myxobacter AL-1 proteinase I
- EC 3.4.99.30: Transferred entry: Myxobacter AL-1 proteinase II. Now EC 3.4.24.20, peptidyl-Lys metalloendopeptidase
- EC 3.4.99.31: Transferred entry: tissue endopeptidase degrading collagenase synthetic substrate. Now EC 3.4.24.15, thimet oligopeptidase
- EC 3.4.99.32: Transferred entry: Armillaria mellea neutral proteinase. Now EC 3.4.24.20, peptidyl-Lys metalloendopeptidase
- EC 3.4.99.33: Deleted entry: cathepsin R
- EC 3.4.99.34: Deleted entry: mytilidase
- EC 3.4.99.35: Transferred entry: premurein-leader peptidase. Now EC 3.4.23.36, signal peptidase II
- EC 3.4.99.36: Transferred entry: leader peptidase. Now EC 3.4.21.89, signal peptidase I
- EC 3.4.99.37: Deleted entry: RecA peptidase
- EC 3.4.99.38: Transferred entry: pro-opiomelanotropin-converting proteinase. Now EC 3.4.23.17, pro-opiomelanocortin converting enzyme
- EC 3.4.99.39: Deleted entry: pseudomurein endopeptidase
- EC 3.4.99.40: Deleted entry: pro-gonadoliberin proteinase
- EC 3.4.99.41: Transferred entry: mitochondrial processing peptidase. Now EC 3.4.24.64, mitochondrial processing peptidase
- EC 3.4.99.42: Deleted entry: leucyllysine endopeptidase
- EC 3.4.99.43: Transferred entry: thermopsin. Now EC 3.4.23.42, thermopsin
- EC 3.4.99.44: Transferred entry: pitrilysin. Now EC 3.4.24.55, pitrilysin
- EC 3.4.99.45: Transferred entry: insulinase. Now EC 3.4.24.56, insulysin
- EC 3.4.99.46: Transferred entry: multicatalytic endopeptidase complex. Now EC 3.4.25.1, proteasome endopeptidase complex
EC 3.5: act on carbon-nitrogen bonds, other than peptide bonds
3.5.1: linear amides
- EC 3.5.1.1: asparaginase
- EC 3.5.1.2: glutaminase
- EC 3.5.1.3: omega-amidase
- EC 3.5.1.4: amidase
- EC 3.5.1.5: urease
- EC 3.5.1.6: beta-ureidopropionase
- EC 3.5.1.7: ureidosuccinase
- EC 3.5.1.8: formylaspartate deformylase
- EC 3.5.1.9: arylformamidase
- EC 3.5.1.10: formyltetrahydrofolate deformylase
- EC 3.5.1.11: penicillin amidase
- EC 3.5.1.12: biotinidase
- EC 3.5.1.13: aryl-acylamidase
- EC 3.5.1.14: aminoacylase
- EC 3.5.1.15: aspartoacylase
- EC 3.5.1.16: acetylornithine deacetylase
- EC 3.5.1.17: acyl-lysine deacylase
- EC 3.5.1.18: succinyl-diaminopimelate desuccinylase
- EC 3.5.1.19: nicotinamidase
- EC 3.5.1.20: citrullinase
- EC 3.5.1.21: N-acetyl-beta-alanine deacetylase
- EC 3.5.1.22: pantothenase
- EC 3.5.1.23: ceramidase
- EC 3.5.1.24: choloylglycine hydrolase
- EC 3.5.1.25: N-acetylglucosamine-6-phosphate deacetylase
- EC 3.5.1.26: N4-(beta-N-acetylglucosaminyl)-L-asparaginase
- EC 3.5.1.27: N-formylmethionylaminoacyl-tRNA deformylase
- EC 3.5.1.28: N-acetylmuramoyl-L-alanine amidase
- EC 3.5.1.29: 2-(acetamidomethylene)succinate hydrolase
- EC 3.5.1.30: 5-aminopentanamidase
- EC 3.5.1.31: formylmethionine deformylase
- EC 3.5.1.32: hippurate hydrolase
- EC 3.5.1.33: N-acetylglucosamine deacetylase
- EC 3.5.1.34: acetylhistidine deacetylase
- EC 3.5.1.35: D-glutaminase
- EC 3.5.1.36: N-methyl-2-oxoglutaramate hydrolase
- EC 3.5.1.37: Deleted entry: 4-L-aspartylglycosylamine amidohydrolase. Identical with EC 3.5.1.26 N4-(β-N-acetylglucosaminyl)-L-asparaginase
- EC 3.5.1.38: glutamin-(asparagin-)ase
- EC 3.5.1.39: alkylamidase
- EC 3.5.1.40: acylagmatine amidase
- EC 3.5.1.41: chitin deacetylase
- EC 3.5.1.42: nicotinamide-nucleotide amidase
- EC 3.5.1.43: peptidyl-glutaminase
- EC 3.5.1.44: protein-glutamine glutaminase
- EC 3.5.1.45: Deleted entry: urease (ATP-hydrolysing). Now listed only as EC 6.3.4.6 urea carboxylase
- EC 3.5.1.46: 6-aminohexanoate-dimer hydrolase
- EC 3.5.1.47: N-acetyldiaminopimelate deacetylase
- EC 3.5.1.48: acetylspermidine deacetylase
- EC 3.5.1.49: formamidase
- EC 3.5.1.50: pentanamidase
- EC 3.5.1.51: 4-acetamidobutyryl-CoA deacetylase
- EC 3.5.1.52: peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase
- EC 3.5.1.53: N-carbamoylputrescine amidase
- EC 3.5.1.54: allophanate hydrolase
- EC 3.5.1.55: long-chain-fatty-acyl-glutamate deacylase
- EC 3.5.1.56: N,N-dimethylformamidase
- EC 3.5.1.57: tryptophanamidase
- EC 3.5.1.58: N-benzyloxycarbonylglycine hydrolase
- EC 3.5.1.59: N-carbamoylsarcosine amidase
- EC 3.5.1.60: N-(long-chain-acyl)ethanolamine deacylase
- EC 3.5.1.61: mimosinase
- EC 3.5.1.62: acetylputrescine deacetylase
- EC 3.5.1.63: 4-acetamidobutyrate deacetylase
- EC 3.5.1.64: Nalpha-benzyloxycarbonylleucine hydrolase
- EC 3.5.1.65: theanine hydrolase
- EC 3.5.1.66: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
- EC 3.5.1.67: 4-methyleneglutaminase
- EC 3.5.1.68: N-formylglutamate deformylase
- EC 3.5.1.69: glycosphingolipid deacylase
- EC 3.5.1.70: aculeacin-A deacylase
- EC 3.5.1.71: N-feruloylglycine deacylase
- EC 3.5.1.72: D-benzoylarginine-4-nitroanilide amidase
- EC 3.5.1.73: carnitinamidase
- EC 3.5.1.74: chenodeoxycholoyltaurine hydrolase
- EC 3.5.1.75: urethanase
- EC 3.5.1.76: Arylalkyl acylamidase
- EC 3.5.1.77: N-carbamoyl-D-amino acid hydrolase
- EC 3.5.1.78: Glutathionylspermidine amidase
- EC 3.5.1.79: Phthalyl amidase
- EC 3.5.1.80: Deleted entry: N-acetylgalactosamine-6-phosphate deacetylase. Identical to EC 3.5.1.25, N-acetylglucosamine-6-phosphate deacetylase
- EC 3.5.1.81: N-acyl-D-amino-acid deacylase
- EC 3.5.1.82: N-acyl-D-glutamate deacylase
- EC 3.5.1.83: N-acyl-D-aspartate deacylase
- EC 3.5.1.84: biuret amidohydrolase
- EC 3.5.1.85: (S)-N-acetyl-1-phenylethylamine hydrolase
- EC 3.5.1.86: mandelamide amidase
- EC 3.5.1.87: N-carbamoyl-L-amino-acid hydrolase
- EC 3.5.1.88: peptide deformylase
- EC 3.5.1.89: N-acetylglucosaminylphosphatidylinositol deacetylase
- EC 3.5.1.90: adenosylcobinamide hydrolase
- EC 3.5.1.91: N-substituted formamide deformylase
- EC 3.5.1.92: pantetheine hydrolase
- EC 3.5.1.93: glutaryl-7-aminocephalosporanic-acid acylase
- EC 3.5.1.94: gamma-glutamyl-gamma-aminobutyrate hydrolase
- EC 3.5.1.95: N-malonylurea hydrolase
- EC 3.5.1.96: succinylglutamate desuccinylase
- EC 3.5.1.97: acyl-homoserine-lactone acylase
- EC 3.5.1.98: histone deacetylase
- EC 3.5.1.99: fatty acid amide hydrolase
- EC 3.5.1.100: (R)-amidase
- EC 3.5.1.101: L-proline amide hydrolase
- EC 3.5.1.102: 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
- EC 3.5.1.103: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase
- EC 3.5.1.104: peptidoglycan-N-acetylglucosamine deacetylase
- EC 3.5.1.105: chitin disaccharide deacetylase
- EC 3.5.1.106: N-formylmaleamate deformylase
- EC 3.5.1.107: maleamate amidohydrolase
- EC 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase
- EC 3.5.1.109: sphingomyelin deacylase
- EC 3.5.1.110: peroxyureidoacrylate/ureidoacrylate amidohydrolase
- EC 3.5.1.111: 2-oxoglutaramate amidase
- EC 3.5.1.112: 2'-N-acetylparomamine deacetylase
- EC 3.5.1.113: 2'''-acetyl-6'''-hydroxyneomycin C deacetylase
3.5.2: cyclic amides
- EC 3.5.2.1: barbiturase
- EC 3.5.2.2: dihydropyrimidinase
- EC 3.5.2.3: dihydroorotase
- EC 3.5.2.4: carboxymethylhydantoinase
- EC 3.5.2.5: allantoinase
- EC 3.5.2.6: beta-lactamase
- EC 3.5.2.7: imidazolonepropionase
- EC 3.5.2.8: Deleted entry: cephalosporinase. Now included with EC 3.5.2.6 β-lactamase
- EC 3.5.2.9: 5-oxoprolinase (ATP-hydrolysing)
- EC 3.5.2.10: creatininase
- EC 3.5.2.11: L-lysine-lactamase
- EC 3.5.2.12: 6-aminohexanoate-cyclic-dimer hydrolase
- EC 3.5.2.13: 2,5-dioxopiperazine hydrolase
- EC 3.5.2.14: N-methylhydantoinase (ATP-hydrolysing)
- EC 3.5.2.15: cyanuric acid amidohydrolase
- EC 3.5.2.16: maleimide hydrolase
- EC 3.5.2.17: hydroxyisourate hydrolase
- EC 3.5.2.18: enamidase
- EC 3.5.2.19: streptothricin hydrolase
3.5.3: linear amidines
- EC 3.5.3.1: arginase
- EC 3.5.3.2: guanidinoacetase
- EC 3.5.3.3: creatinase
- EC 3.5.3.4: allantoicase
- EC 3.5.3.5: formimidoylaspartate deiminase
- EC 3.5.3.6: arginine deiminase
- EC 3.5.3.7: guanidinobutyrase
- EC 3.5.3.8: formimidoylglutamase
- EC 3.5.3.9: allantoate deiminase
- EC 3.5.3.10: D-arginase
- EC 3.5.3.11: agmatinase
- EC 3.5.3.12: agmatine deiminase
- EC 3.5.3.13: formimidoylglutamate deiminase
- EC 3.5.3.14: amidinoaspartase
- EC 3.5.3.15: protein-arginine deiminase
- EC 3.5.3.16: methylguanidinase
- EC 3.5.3.17: Guanidinopropionase
- EC 3.5.3.18: dimethylargininase
- EC 3.5.3.19: ureidoglycolate hydrolase
- EC 3.5.3.20: diguanidinobutanase
- EC 3.5.3.21: Methylenediurea deaminase
- EC 3.5.3.22: proclavaminate amidinohydrolase
- EC 3.5.3.23: N-succinylarginine dihydrolase
3.5.4: cyclic amidines
- EC 3.5.4.1: cytosine deaminase
- EC 3.5.4.2: adenine deaminase
- EC 3.5.4.3: guanine deaminase
- EC 3.5.4.4: adenosine deaminase
- EC 3.5.4.5: cytidine deaminase
- EC 3.5.4.6: AMP deaminase
- EC 3.5.4.7: ADP deaminase
- EC 3.5.4.8: aminoimidazolase
- EC 3.5.4.9: methenyltetrahydrofolate cyclohydrolase
- EC 3.5.4.10: IMP cyclohydrolase
- EC 3.5.4.11: pterin deaminase
- EC 3.5.4.12: dCMP deaminase
- EC 3.5.4.13: dCTP deaminase
- EC 3.5.4.14: deoxycytidine deaminase
- EC 3.5.4.15: guanosine deaminase
- EC 3.5.4.16: GTP cyclohydrolase I
- EC 3.5.4.17: adenosine-phosphate deaminase
- EC 3.5.4.18: ATP deaminase
- EC 3.5.4.19: phosphoribosyl-AMP cyclohydrolase
- EC 3.5.4.20: pyrithiamine deaminase
- EC 3.5.4.21: creatinine deaminase
- EC 3.5.4.22: 1-pyrroline-4-hydroxy-2-carboxylate deaminase
- EC 3.5.4.23: blasticidin-S deaminase
- EC 3.5.4.24: sepiapterin deaminase
- EC 3.5.4.25: GTP cyclohydrolase II
- EC 3.5.4.26: diaminohydroxyphosphoribosylaminopyrimidine deaminase
- EC 3.5.4.27: methenyltetrahydromethanopterin cyclohydrolase
- EC 3.5.4.28: S-adenosylhomocysteine deaminase
- EC 3.5.4.29: GTP cyclohydrolase IIa
- EC 3.5.4.30: dCTP deaminase (dUMP-forming)
- EC 3.5.4.31: S-methyl-5'-thioadenosine deaminase
- EC 3.5.4.32: 8-oxoguanine deaminase
3.5.5: nitriles
- EC 3.5.5.1: nitrilase
- EC 3.5.5.2: ricinine nitrilase
- EC 3.5.5.3: Transferred entry: cyanate hydrolase. Now EC 4.2.1.104, cyanate hydratase
- EC 3.5.5.4: cyanoalanine nitrilase
- EC 3.5.5.5: arylacetonitrilase
- EC 3.5.5.6: bromoxynil nitrilase
- EC 3.5.5.7: aliphatic nitrilase
- EC 3.5.5.8: thiocyanate hydrolase
3.5.99: other compounds
- EC 3.5.99.1: riboflavinase
- EC 3.5.99.2: aminopyrimidine aminohydrolase
- EC 3.5.99.3: hydroxydechloroatrazine ethylaminohydrolase
- EC 3.5.99.4: N-isopropylammelide isopropylaminohydrolase
- EC 3.5.99.5: 2-aminomuconate deaminase
- EC 3.5.99.6: glucosamine-6-phosphate deaminase
- EC 3.5.99.7: 1-aminocyclopropane-1-carboxylate deaminase
- EC 3.5.99.8: 5-nitroanthranilic acid aminohydrolase
- EC 3.5.99.9: 2-nitroimidazole nitrohydrolase
EC 3.6: Act on acid anhydrides
3.6.1
- EC 3.6.1.1: inorganic diphosphatase
- EC 3.6.1.2: trimetaphosphatase
- EC 3.6.1.3: adenosinetriphosphatase
- EC 3.6.1.4: Deleted entry: adenosinetriphosphatase (Mg-activated). Now included with EC 3.6.1.3 adenosinetriphosphatase
- EC 3.6.1.5: apyrase
- EC 3.6.1.6: nucleoside-diphosphatase
- EC 3.6.1.7: acylphosphatase
- EC 3.6.1.8: ATP diphosphatase
- EC 3.6.1.9: nucleotide diphosphatase
- EC 3.6.1.10: endopolyphosphatase
- EC 3.6.1.11: exopolyphosphatase
- EC 3.6.1.12: dCTP diphosphatase
- EC 3.6.1.13: ADP-ribose diphosphatase
- EC 3.6.1.14: adenosine-tetraphosphatase
- EC 3.6.1.15: nucleoside-triphosphatase
- EC 3.6.1.16: CDP-glycerol diphosphatase
- EC 3.6.1.17: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
- EC 3.6.1.18: FAD diphosphatase
- EC 3.6.1.19: nucleoside-triphosphate diphosphatase
- EC 3.6.1.20: 5'-acylphosphoadenosine hydrolase
- EC 3.6.1.21: ADP-sugar diphosphatase
- EC 3.6.1.22: NAD+ diphosphatase
- EC 3.6.1.23: dUTP diphosphatase
- EC 3.6.1.24: nucleoside phosphoacylhydrolase
- EC 3.6.1.25: triphosphatase
- EC 3.6.1.26: CDP-diacylglycerol diphosphatase
- EC 3.6.1.27: undecaprenyl-diphosphatase
- EC 3.6.1.28: thiamine-triphosphatase
- EC 3.6.1.29: bis(5'-adenosyl)-triphosphatase
- EC 3.6.1.30: m7G(5')pppN diphosphatase
- EC 3.6.1.31: phosphoribosyl-ATP diphosphatase
- EC 3.6.1.32: Transferred entry: myosin ATPase. Now EC 3.6.4.1, myosin ATPase
- EC 3.6.1.33: Transferred entry: dynein ATPase. Now EC 3.6.4.2, dynein ATPase
- EC 3.6.1.34: Transferred entry: H+-transporting ATP synthase. Now EC 3.6.3.14, H+-transporting two-sector ATPase
- EC 3.6.1.35: Transferred entry: H+-transporting ATPase. Now EC 3.6.3.6, H+-exporting ATPase
- EC 3.6.1.36: Transferred entry: H+/K+ exchanging ATPase. Now EC 3.6.3.10, H+/K+-exchanging ATPase
- EC 3.6.1.37: Transferred entry: Na+/K+ exchanging ATPase. Now EC 3.6.3.9, Na+/K+-exchanging ATPase
- EC 3.6.1.38: Transferred entry: Ca2+-transporting ATPase. Now EC 3.6.3.8, Ca2+-transporting ATPase
- EC 3.6.1.39: thymidine-triphosphatase
- EC 3.6.1.40: guanosine-5'-triphosphate,3'-diphosphate diphosphatase
- EC 3.6.1.41: bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
- EC 3.6.1.42: guanosine-diphosphatase
- EC 3.6.1.43: dolichyldiphosphatase
- EC 3.6.1.44: oligosaccharide-diphosphodolichol diphosphatase
- EC 3.6.1.45: UDP-sugar diphosphatase
- EC 3.6.1.46: Transferred entry: heterotrimeric G-protein GTPase. Now EC 3.6.5.1, heterotrimeric G-protein GTPase
- EC 3.6.1.47: Transferred entry: small monomeric GTPase. Now EC 3.6.5.2, small monomeric GTPase
- EC 3.6.1.48: Transferred entry: protein-synthesizing GTPase. Now EC 3.6.5.3, protein-synthesizing GTPase
- EC 3.6.1.49: Transferred entry: signal-recognition-particle GTPase. Now EC 3.6.5.4, signal-recognition-particle GTPase
- EC 3.6.1.50: Transferred entry: dynamin GTPase. Now EC 3.6.5.5, dynamin GTPase
- EC 3.6.1.51: Transferred entry: tubulin GTPase. Now EC 3.6.5.6, tubulin GTPase
- EC 3.6.1.52: diphosphoinositol-polyphosphate diphosphatase
- EC 3.6.1.53: Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
- EC 3.6.1.54: UDP-2,3-diacylglucosamine diphosphatase
- EC 3.6.1.55: 8-oxo-dGTP diphosphatase
- EC 3.6.1.56: 2-hydroxy-dATP diphosphatase
- EC 3.6.1.57: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase
- EC 3.6.1.58: 8-oxo-dGDP phosphatase
- EC 3.6.1.59: m7GpppX diphosphatase
- EC 3.6.1.60: diadenosine hexaphosphate hydrolase (AMP-forming)
- EC 3.6.1.61: diadenosine hexaphosphate hydrolase (ATP-forming)
- EC 3.6.1.62: m7GpppN-mRNA hydrolase
- EC 3.6.1.63: alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
3.6.3
- EC 3.6.3.1: phospholipid-translocating ATPase
- EC 3.6.3.2: Mg2+-importing ATPase
- EC 3.6.3.3: Cd2+-exporting ATPase
- EC 3.6.3.4: Cu2+-exporting ATPase
- EC 3.6.3.5: Zn2+-exporting ATPase
- EC 3.6.3.6: H+-exporting ATPase
- EC 3.6.3.7: Na+-exporting ATPase
- EC 3.6.3.8: Ca2+-transporting ATPase
- EC 3.6.3.9: Na+/K+-exchanging ATPase
- EC 3.6.3.10: H+/K+-exchanging ATPase
- EC 3.6.3.11: Cl-transporting ATPase
- EC 3.6.3.12: K+-transporting ATPase
- EC 3.6.3.14: H+-transporting two-sector ATPase
- EC 3.6.3.15: Na+-transporting two-sector ATPase
- EC 3.6.3.16: arsenite-transporting ATPase
- EC 3.6.3.17: monosaccharide-transporting ATPase
- EC 3.6.3.18: oligosaccharide-transporting ATPase
- EC 3.6.3.19: maltose-transporting ATPase
- EC 3.6.3.20: glycerol-3-phosphate-transporting ATPase
- EC 3.6.3.21: polar-amino-acid-transporting ATPase
- EC 3.6.3.22: nonpolar-amino-acid-transporting ATPase
- EC 3.6.3.23: oligopeptide-transporting ATPase
- EC 3.6.3.24: nickel-transporting ATPase
- EC 3.6.3.25: sulfate-transporting ATPase
- EC 3.6.3.26: nitrate-transporting ATPase
- EC 3.6.3.27: phosphate-transporting ATPase
- EC 3.6.3.28: phosphonate-transporting ATPase
- EC 3.6.3.29: molybdate-transporting ATPase
- EC 3.6.3.30: Fe3+-transporting ATPase
- EC 3.6.3.31: polyamine-transporting ATPase
- EC 3.6.3.32: quaternary-amine-transporting ATPase
- EC 3.6.3.33: vitamin B12-transporting ATPase
- EC 3.6.3.34: iron-chelate-transporting ATPase
- EC 3.6.3.35: manganese-transporting ATPase
- EC 3.6.3.36: taurine-transporting ATPase
- EC 3.6.3.37: guanine-transporting ATPase
- EC 3.6.3.38: capsular-polysaccharide-transporting ATPase
- EC 3.6.3.39: lipopolysaccharide-transporting ATPase
- EC 3.6.3.40: teichoic-acid-transporting ATPase
- EC 3.6.3.41: heme-transporting ATPase
- EC 3.6.3.42: beta-glucan-transporting ATPase
- EC 3.6.3.43: peptide-transporting ATPase
- EC 3.6.3.44: xenobiotic-transporting ATPase
- EC 3.6.3.45: steroid-transporting ATPase
- EC 3.6.3.46: cadmium-transporting ATPase
- EC 3.6.3.47: fatty-acyl-CoA-transporting ATPase
- EC 3.6.3.48: alpha-factor-transporting ATPase
- EC 3.6.3.49: channel-conductance-controlling ATPase
- EC 3.6.3.50: protein-secreting ATPase
- EC 3.6.3.51: mitochondrial protein-transporting ATPase
- EC 3.6.3.52: chloroplast protein-transporting ATPase
- EC 3.6.3.53: Ag+-exporting ATPase
3.6.4
- EC 3.6.4.1: myosin ATPase
- EC 3.6.4.2: dynein ATPase
- EC 3.6.4.3: microtubule-severing ATPase
- EC 3.6.4.4: plus-end-directed kinesin ATPase
- EC 3.6.4.5: minus-end-directed kinesin ATPase
- EC 3.6.4.6: vesicle-fusing ATPase
- EC 3.6.4.7: peroxisome-assembly ATPase
- EC 3.6.4.8: proteasome ATPase
- EC 3.6.4.9: chaperonin ATPase
- EC 3.6.4.10: non-chaperonin molecular chaperone ATPase
- EC 3.6.4.11: nucleoplasmin ATPase
- EC 3.6.4.12: DNA helicase
- EC 3.6.4.13: RNA helicase
3.6.5
- EC 3.6.5.1: heterotrimeric G-protein GTPase
- EC 3.6.5.2: small monomeric GTPase
- EC 3.6.5.3: protein-synthesizing GTPase
- EC 3.6.5.4: signal-recognition-particle GTPase
- EC 3.6.5.5: dynamin GTPase
- EC 3.6.5.6: tubulin GTPase
EC 3.7: act on carbon-carbon bonds
- EC 3.7.1.1: oxaloacetase
- EC 3.7.1.2: fumarylacetoacetase
- EC 3.7.1.3: kynureninase
- EC 3.7.1.4: phloretin hydrolase
- EC 3.7.1.5: acylpyruvate hydrolase
- EC 3.7.1.6: acetylpyruvate hydrolase
- EC 3.7.1.7: beta-diketone hydrolase
- EC 3.7.1.8: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
- EC 3.7.1.9: 2-hydroxymuconate-semialdehyde hydrolase
- EC 3.7.1.10: cyclohexane-1,3-dione hydrolase
- EC 3.7.1.11: cyclohexane-1,2-dione hydrolase
- EC 3.7.1.12: cobalt-precorrin 5A hydrolase
- EC 3.7.1.13: 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
- EC 3.7.1.14: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase
- EC 3.7.1.15: (+)-caryolan-1-ol synthase
- EC 3.7.1.16: oxepin-CoA hydrolase
- EC 3.7.1.17: 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
- EC 3.7.1.18: 6-oxocamphor hydrolase
- EC 3.7.1.19: 2,6-dihydroxypseudooxynicotine hydrolase
- EC 3.7.1.20: 3-fumarylpyruvate hydrolase
EC 3.8: act on halide bonds
- EC 3.8.1.1: alkylhalidase
- EC 3.8.1.2: 2-haloacid dehalogenase
- EC 3.8.1.3: haloacetate dehalogenase
- EC 3.8.1.4: Transferred entry: now EC 1.97.1.10, thyroxine 5'-deiodinase
- EC 3.8.1.5: haloalkane dehalogenase
- EC 3.8.1.6: 4-chlorobenzoate dehalogenase
- EC 3.8.1.7: 4-chlorobenzoyl-CoA dehalogenase
- EC 3.8.1.8: atrazine chlorohydrolase
- EC 3.8.1.9: (R)-2-haloacid dehalogenase
- EC 3.8.1.10: 2-haloacid dehalogenase (configuration-inverting)
- EC 3.8.1.11: 2-haloacid dehalogenase (configuration-retaining)
- EC 3.8.2.1: Transferred entry: di-isopropyl-fluorophosphatase. Now EC 3.1.8.2, diisopropyl-fluorophosphatase
EC 3.9: act on phosphorus-nitrogen bonds
EC 3.10: act on sulfur-nitrogen bonds
EC 3.11: act on carbon-phosphorus bonds
EC 3.12: act on sulfur-sulfur bonds
EC 3.13: act on carbon-sulfur bonds
- EC 3.13.1.1: UDP-sulfoquinovose synthase
- EC 3.13.1.2: Deleted entry: 5-deoxyribos-5-ylhomocysteinase. The activity is most probably attributable to EC 4.4.1.21, S-ribosylhomocysteine lyase
- EC 3.13.1.3: 2'-hydroxybiphenyl-2-sulfinate desulfinase
- EC 3.13.1.4: 3-sulfinopropanoyl-CoA desulfinase
- EC 3.13.1.5: Carbon disulfide hydrolase
- EC 3.13.1.6: [[[CysO sulfur-carrier protein]-S-L-cysteine hydrolase]]
- EC 3.13.1.7: Carbonyl sulfide hydrolase
- EC 3.13.1.8: S-adenosyl-L-methionine hydrolase (adenosine-forming)
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