DNA-deoxyinosine glycosylase
DNA-deoxyinosine glycosylase (EC 3.2.2.15, DNA(hypoxanthine) glycohydrolase, deoxyribonucleic acid glycosylase, hypoxanthine-DNA glycosylase) is an enzyme with systematic name DNA-deoxyinosine deoxyribohydrolase.[1] This enzyme catalyses the following chemical reaction
- Hydrolyses DNA and polynucleotides, releasing free hypoxanthine
| DNA-deoxyinosine glycosylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.2.15 | ||||||||
| CAS number | 68247-62-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
References
- Karran P, Lindahl T (September 1978). "Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues". The Journal of Biological Chemistry. 253 (17): 5877–9. PMID 98523.
External links
- DNA-deoxyinosine+glycosylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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