Aminopeptidase Y

Aminopeptidase Y (EC 3.4.11.15, aminopeptidase Co, aminopeptidase (cobalt-activated), lysyl aminopeptidase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Preferentially, release of N-terminal lysine
Aminopeptidase Y
Lysyl aminopeptidase dodekamer, Pyrococcus furiosus
Identifiers
EC number3.4.11.15
CAS number114796-97-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme requires Co2+. It is inhibited by Zn2+ and Mn2+.

References

  1. Achstetter T, Ehmann C, Wolf DH (November 1982). "Aminopeptidase Co, a new yeast peptidase". Biochemical and Biophysical Research Communications. 109 (2): 341–7. doi:10.1016/0006-291x(82)91726-0. PMID 6758786.
  2. Yasuhara T, Nakai T, Ohashi A (May 1994). "Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B". The Journal of Biological Chemistry. 269 (18): 13644–50. PMID 8175799.
  3. Nishizawa M, Yasuhara T, Nakai T, Fujiki Y, Ohashi A (May 1994). "Molecular cloning of the aminopeptidase Y gene of Saccharomyces cerevisiae. Sequence analysis and gene disruption of a new aminopeptidase". The Journal of Biological Chemistry. 269 (18): 13651–5. PMID 8175800.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.