2,3-bisphosphoglycerate 3-phosphatase

2,3-bisphosphoglycerate 3-phosphatase (EC 3.1.3.80, MIPP1, 2,3-BPG 3-phosphatase) is an enzyme with systematic name 2,3-bisphospho-D-glycerate 3-phosphohydrolase.[1] This enzyme catalyses the following chemical reaction

2,3-bisphospho-D-glycerate + H2O 2-phospho-D-glycerate + phosphate
2,3-bisphosphoglycerate 3-phosphatase
Identifiers
EC number3.1.3.80
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This reaction is a shortcut in the Luebering-Rapoport pathway.

References

  1. Cho J, King JS, Qian X, Harwood AJ, Shears SB (April 2008). "Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt". Proceedings of the National Academy of Sciences of the United States of America. 105 (16): 5998–6003. doi:10.1073/pnas.0710980105. PMC 2329705. PMID 18413611.
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