Oligosaccharide-diphosphodolichol diphosphatase

In enzymology, an oligosaccharide-diphosphodolichol diphosphatase (EC 3.6.1.44) is an enzyme that catalyzes the chemical reaction

oligosaccharide-diphosphodolichol + H2O oligosaccharide phosphate + dolichyl phosphate
oligosaccharide-diphosphodolichol diphosphatase
Identifiers
EC number3.6.1.44
CAS number117698-28-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are oligosaccharide-diphosphodolichol and H2O, whereas its two products are oligosaccharide phosphate and dolichyl phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is oligosaccharide-diphosphodolichol phosphodolichohydrolase. This enzyme is also called oligosaccharide-diphosphodolichol pyrophosphatase.

References

    • Belard M, Cacan R, Verbert A (1988). "Characterization of an oligosaccharide-pyrophosphodolichol pyrophosphatase activity in yeast". Biochem. J. 255 (1): 235–42. PMC 1135215. PMID 2848504.


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