Stromelysin 2

Stromelysin 2 (EC 3.4.24.22, matrix metalloproteinase 10, transin 2, proteoglycanase 2) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Similar to stromelysin 1, but action on collagen types III, IV and V is weak
Stromelysin 2
Identifiers
EC number3.4.24.22
CAS number140610-48-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme belongs to the peptidase family M10 (interstitial collagenase family).

References

  1. Breathnach R, Matrisian LM, Gesnel MC, Staub A, Leroy P (February 1987). "Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene". Nucleic Acids Research. 15 (3): 1139–51. doi:10.1093/nar/15.3.1139. PMC 340513. PMID 3547333.
  2. Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R (July 1988). "The collagenase gene family in humans consists of at least four members". The Biochemical Journal. 253 (1): 187–92. doi:10.1042/bj2530187. PMC 1149273. PMID 2844164.
  3. Nicholson R, Murphy G, Breathnach R (June 1989). "Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases". Biochemistry. 28 (12): 5195–203. doi:10.1021/bi00438a042. PMID 2548603.
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