CDP-diacylglycerol diphosphatase
In enzymology, a CDP-diacylglycerol diphosphatase (EC 3.6.1.26) is an enzyme that catalyzes the chemical reaction
- CDP-diacylglycerol + H2O CMP + phosphatidate
CDP-diacylglycerol diphosphatase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 3.6.1.26 | ||||||||
CAS number | 62213-20-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
Thus, the two substrates of this enzyme are CDP-diacylglycerol and H2O, whereas its two products are CMP and phosphatidate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is CDP-diacylglycerol phosphatidylhydrolase. Other names in common use include cytidine diphosphodiacylglycerol pyrophosphatase, and CDP diacylglycerol hydrolase. This enzyme participates in glycerophospholipid metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2POF.
gollark: My Minecraft bases are either just holes in the ground or giant cubes with overly tall glass windows.
gollark: I, for one, like glass and concrete cubes.
gollark: The what? Oh no.
gollark: Through layer upon layer of horrible, horrible hacks, yes, it kind of works.
gollark: They're both OFDMA-based, admittedly use somewhat different frequency ranges, just carry IP packets nowadays, are increasingly going for ridiculous data rates, are often implemented in the same devices, that sort of thing.
References
- Raetz CR, Hirschberg CB, Dowhan W, Wickner WT, Kennedy EP (1972). "A membrane-bound pyrophosphatase in Escherichia coli catalyzing the hydrolysis of cytidine diphosphate-diglyceride". J. Biol. Chem. 247 (7): 2245–7. PMID 4335869.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.