Atroxase

Atroxase (EC 3.4.24.43) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of His5-Leu, Ser9-His, His10-Leu, Ala14-Leu and Tyr16-Leu of insulin B chain
Atroxase
Identifiers
EC number3.4.24.43
CAS number181186-94-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).

References

  1. Willis TW, Tu AT (June 1988). "Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom". Biochemistry. 27 (13): 4769–77. doi:10.1021/bi00413a028. PMID 3167016.
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