(pyruvate kinase)-phosphatase
In enzymology, a [pyruvate kinase]-phosphatase (EC 3.1.3.49) is an enzyme that catalyzes the chemical reaction
- [pyruvate kinase] phosphate + H2O [pyruvate kinase] + phosphate
| [pyruvate kinase]-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.49 | ||||||||
| CAS number | 79986-25-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are pyruvate kinase phosphate and H2O, whereas its two products are pyruvate kinase and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is [ATP:pyruvate 2-O-phosphotransferase]-phosphate phosphohydrolase. This enzyme is also called pyruvate kinase phosphatase.
References
- Jett MF, Hue L, Hers HG (1981). "Pyruvate kinase phosphatase". FEBS Lett. 132 (2): 183–6. doi:10.1016/0014-5793(81)81156-8. PMID 6271587.
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