Spleen exonuclease

Spleen exonuclease (EC 3.1.16.1, 3'-exonuclease, spleen phosphodiesterase, 3'-nucleotide phosphodiesterase, phosphodiesterase II) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates (exonuclease type b)
Spleen exonuclease
Identifiers
EC number3.1.16.1
CAS number9068-54-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme has a preference for single-stranded substrate.

References

  1. Bernardi A, Bernardi G (1971). "Spleen acid nuclease". In Boyer PD (ed.). The Enzymes. 4 (3rd ed.). New York: Academic Press. pp. 329–336.
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