Deoxylimonate A-ring-lactonase

In enzymology, a deoxylimonate A-ring-lactonase (EC 3.1.1.46) is an enzyme that catalyzes the chemical reaction

deoxylimonate + H2O deoxylimononic acid D-ring-lactone
deoxylimonate A-ring-lactonase
Identifiers
EC number3.1.1.46
CAS number75788-82-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are deoxylimonate and H2O, whereas its product is deoxylimononic acid D-ring-lactone.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is deoxylimonate A-ring-lactonohydrolase.

References

    • Hasegawa H, Bennett RD, Verdon CP (1980). "Metabolism of limonoids via a deoxylimonoid pathway in Citrus". Phytochemistry. 19: 1445–1447. doi:10.1016/0031-9422(80)80191-9.
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