Aqualysin 1
Aqualysin 1 (EC 3.4.21.111, caldolysin) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Exhibits low specificity towards esters of amino acids with small hydrophobic or aromatic residues at the P1 position
| Aqualysin 1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.21.111 | ||||||||
| CAS number | 88747-68-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is isolated from the thermophile, Thermus aquaticus.
References
- Matsuzawa H, Tokugawa K, Hamaoki M, Mizoguchi M, Taguchi H, Terada I, Kwon ST, Ohta T (February 1988). "Purification and characterization of aqualysin I (a thermophilic alkaline serine protease) produced by Thermus aquaticus YT-1". European Journal of Biochemistry. 171 (3): 441–7. doi:10.1111/j.1432-1033.1988.tb13809.x. PMID 3162211.
- Tanaka T, Matsuzawa H, Kojima S, Kumagai I, Miura K, Ohta T (October 1998). "P1 specificity of aqualysin I (a subtilisin-type serine protease) from Thermus aquaticus YT-1, using P1-substituted derivatives of Streptomyces subtilisin inhibitor". Bioscience, Biotechnology, and Biochemistry. 62 (10): 2035–8. doi:10.1271/bbb.62.2035. PMID 9882104.
- Tanaka T, Matsuzawa H, Ohta T (1998). "Substrate Specificity of Aqualysin I, a Bacterial Thermophilic Alkaline Serine Protease from Thermus aquaticus YT-1: Comparison with Proteinase K, Subtilisin BPN' and Subtilisin Carlsberg". Bioscience, Biotechnology, and Biochemistry. 62 (11): 2161–5. doi:10.1271/bbb.62.2161.
External links
- Aqualysin+1 at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.