Semenogelase
Semenogelase (EC 3.4.21.77, prostate-specific antigen, alpha-seminoprotein, seminin, P-30 antigen, antigen (human clone HPSA-1 prostate-specific protein moiety reduced), gamma-seminoglycoprotein (human protein moiety reduced), gamma-SM, antigen PSA (human prostate-specific), human glandular kallikrein, antigen PSA (human clone 5P1 protein moiety reduced)) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Preferential cleavage: -Tyr-
| Semenogelase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.21.77 | ||||||||
| CAS number | 95829-41-7&title= 110157-83-0, 95829-41-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This peptidase from trypsin family is present in seminal plasma.
See also
References
- Digby M, Zhang XY, Richards RI (March 1989). "Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1". Nucleic Acids Research. 17 (5): 2137. doi:10.1093/nar/17.5.2137. PMC 317563. PMID 2467258.
- Christensson A, Laurell CB, Lilja H (December 1990). "Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors". European Journal of Biochemistry. 194 (3): 755–63. doi:10.1111/j.1432-1033.1990.tb19466.x. PMID 1702714.
External links
- Semenogelase at the US National Library of Medicine Medical Subject Headings (MeSH)
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