Semenogelase

Semenogelase (EC 3.4.21.77, prostate-specific antigen, alpha-seminoprotein, seminin, P-30 antigen, antigen (human clone HPSA-1 prostate-specific protein moiety reduced), gamma-seminoglycoprotein (human protein moiety reduced), gamma-SM, antigen PSA (human prostate-specific), human glandular kallikrein, antigen PSA (human clone 5P1 protein moiety reduced)) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Preferential cleavage: -Tyr-
Semenogelase
Identifiers
EC number3.4.21.77
CAS number95829-41-7&title= 110157-83-0, 95829-41-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This peptidase from trypsin family is present in seminal plasma.

See also

References

  1. Digby M, Zhang XY, Richards RI (March 1989). "Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1". Nucleic Acids Research. 17 (5): 2137. doi:10.1093/nar/17.5.2137. PMC 317563. PMID 2467258.
  2. Christensson A, Laurell CB, Lilja H (December 1990). "Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors". European Journal of Biochemistry. 194 (3): 755–63. doi:10.1111/j.1432-1033.1990.tb19466.x. PMID 1702714.
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