Triphosphatase

In enzymology, a triphosphatase (EC 3.6.1.25) is an enzyme that catalyzes the chemical reaction

triphosphate + H2O diphosphate + phosphate
triphosphatase
Identifiers
EC number3.6.1.25
CAS number62213-21-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are triphosphate and H2O, whereas its two products are diphosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is triphosphate phosphohydrolase. This enzyme is also called inorganic triphosphatase.

References

    • Kulaev IS, Konoshenko GI, Umnov AM. "Localization of polyphosphatase hydolyzing polyphosphates to orthophosphate in subcellular structures of Neurospora crassa". Biochemistry. Moscow. 37: 190–194.
    • Umnov AM, Egorov SN, Mansurova SE, Kulaev IS. "A comparative characterisation of the polyphosphatases of Neurospora crassa and some other organisms". Biochemistry. Moscow. 39: 309–312.


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