Uridine nucleosidase
In enzymology, an uridine nucleosidase (EC 3.2.2.3) is an enzyme that catalyzes the chemical reaction
- uridine + H2O D-ribose + uracil
| uridine nucleosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.2.3 | ||||||||
| CAS number | 9025-47-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are uridine and H2O, whereas its two products are D-ribose and uracil.
This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is uridine ribohydrolase. This enzyme is also called uridine hydrolase. This enzyme participates in pyrimidine metabolism.
Structural studies
As of late 2007, 23 structures have been solved for this class of enzymes, with PDB accession codes 1EMH, 1EMJ, 1EUG, 1FLZ, 1OKB, 1SSP, 1UDG, 1UDH, 1UDI, 1UGH, 1UUG, 1YUO, 2BOO, 2C53, 2C56, 2EUG, 2J8X, 2SSP, 2UUG, 3EUG, 4EUG, 4SKN, and 5EUG.
gollark: The remote feature needs SPUDNET keys, and I never bothered to make the channel configurable.
gollark: You need one turtle as a server and as many as you want as clients.
gollark: It uses any chest connected to the network for storage because I was too lazy to design an actual configurator.
gollark: Just run https://osmarks.net/stuff/install.lua and it'll do all the things.
gollark: Okay, confirmed.
References
- Carter CE (1951). "Partial purification of a non-phosphorylytic uridine nucleosidase from yeast". J. Am. Chem. Soc. 73 (4): 1508–1510. doi:10.1021/ja01148a028. hdl:2027/mdp.39015086475954.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.