Gamma-Renin

Gamma-renin (EC 3.4.21.54) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Cleavage of the Leu-Leu bond in synthetic renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen
Gamma-renin
Identifiers
EC number3.4.21.54
CAS number85270-20-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is present in submandibular glands of male mice.

References

  1. Poe M, Wu JK, Florance JR, Rodkey JA, Bennett CD, Hoogsteen K (February 1983). "Purification and properties of renin and gamma-renin from the mouse submaxillary gland". The Journal of Biological Chemistry. 258 (4): 2209–16. PMID 6337154.
  2. Drinkwater CC, Evans BA, Richards RI (June 1988). "Sequence and expression of mouse gamma-renin". The Journal of Biological Chemistry. 263 (18): 8565–8. PMID 3288617.
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