Methylphosphothioglycerate phosphatase

In enzymology, a methylphosphothioglycerate phosphatase (EC 3.1.3.14) is an enzyme that catalyzes the chemical reaction

S-methyl-3-phospho-1-thio-D-glycerate + H2O S-methyl-1-thio-D-glycerate + phosphate
methylphosphothioglycerate phosphatase
Identifiers
EC number3.1.3.14
CAS number9025-78-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are S-methyl-3-phospho-1-thio-D-glycerate and H2O, whereas its two products are S-methyl-1-thio-D-glycerate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase. This enzyme is also called methylthiophosphoglycerate phosphatase.

References

    • Black S, Wright NG (July 1956). "Enzymatic formation of glyceryl and phosphoglyceryl methylthiol esters". The Journal of Biological Chemistry. 221 (1): 171–80. PMID 13345808.


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