Trans-epoxysuccinate hydrolase

In enzymology, a trans-epoxysuccinate hydrolase (EC 3.3.2.4) is an enzyme that catalyzes the chemical reaction

trans-2,3-epoxysuccinate + H2O meso-tartrate
trans-epoxysuccinate hydrolase
Identifiers
EC number3.3.2.4
CAS number37290-73-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are trans-2,3-epoxysuccinate and H2O, whereas its product is meso-tartrate.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is trans-2,3-epoxysuccinate hydrolase. Other names in common use include trans-epoxysuccinate hydratase, and tartrate epoxydase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

    • Allen RH, Jakoby WB (1969). "Tartaric acid metabolism. IX. Synthesis with tartrate epoxidase". J. Biol. Chem. 244 (8): 2078–84. PMID 5782001.


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