Ribonuclease IV
Ribonuclease IV (EC 3.1.26.6, endoribonuclease IV, poly(A)-specific ribonuclease) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups
| Ribonuclease IV | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.26.6 | ||||||||
| CAS number | 61536-76-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme forms oligonucleotides with an average chain length of 10.
References
- Müller WE (November 1976). "Endoribonuclease IV. A poly(A)-specific ribonuclease from chick oviduct. 1. Purification of the enzyme". European Journal of Biochemistry. 70 (1): 241–8. doi:10.1111/j.1432-1033.1976.tb10975.x. PMID 1009928.
- Müller WE, Seibert G, Steffen R, Zahn RK (November 1976). "Endoribonuclease IV. 2. Further investigation on the specificity". European Journal of Biochemistry. 70 (1): 249–58. doi:10.1111/j.1432-1033.1976.tb10976.x. PMID 1009929.
External links
- Ribonuclease+IV at the US National Library of Medicine Medical Subject Headings (MeSH)
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