Exoribonuclease II
Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading), 5'-exoribonuclease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
- Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
| Exoribonuclease II | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.13.1 | ||||||||
| CAS number | 37288-24-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme has preference for single-stranded RNA.
See also
References
- Nossal NG, Singer MF (March 1968). "The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II". The Journal of Biological Chemistry. 243 (5): 913–22. PMID 4867942.
- Schmidt FJ, McClain WH (November 1978). "An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA". Nucleic Acids Research. 5 (11): 4129–39. doi:10.1093/nar/5.11.4129. PMC 342738. PMID 364422.
- Shimura Y, Sakano H, Nagawa F (May 1978). "Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties". European Journal of Biochemistry. 86 (1): 267–81. doi:10.1111/j.1432-1033.1978.tb12308.x. PMID 350582.
- Sporn MB, Lazarus HM, Smith JM, Henderson WR (April 1969). "Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse". Biochemistry. 8 (4): 1698–706. doi:10.1021/bi00832a053. PMID 5805304.
External links
- Exoribonuclease+II at the US National Library of Medicine Medical Subject Headings (MeSH)
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