Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase

Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase (EC 3.6.1.63, phnM (gene)) is an enzyme with systematic name alpha-D-ribose-1-methylphosphonate-5-triphosphate diphosphohydrolase.[1] This enzyme catalyses the following chemical reaction

alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate
Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
Identifiers
EC number3.6.1.63
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from the bacterium Escherichia coli.

References

  1. Kamat SS, Williams HJ, Raushel FM (November 2011). "Intermediates in the transformation of phosphonates to phosphate by bacteria". Nature. 480 (7378): 570–3. doi:10.1038/nature10622. PMC 3245791. PMID 22089136.
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