Hypodermin C

Hypodermin C (EC 3.4.21.49, Hypoderma collagenase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins including native collagen at -Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment
Hypodermin C
Identifiers
EC number3.4.21.49
CAS number122191-36-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is isolated from the larva of a warble fly, Hypoderma lineatum.

References

  1. Lecroisey A, Boulard C, Keil B (November 1979). "Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum". European Journal of Biochemistry. 101 (2): 385–93. doi:10.1111/j.1432-1033.1979.tb19730.x. PMID 230030.
  2. Lecroisey A, Keil B (October 1985). "Specificity of the collagenase from the insect Hypoderma lineatum". European Journal of Biochemistry. 152 (1): 123–30. doi:10.1111/j.1432-1033.1985.tb09171.x. PMID 2995028.
  3. Lecroisey A, Gilles AM, De Wolf A, Keil B (June 1987). "Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum". The Journal of Biological Chemistry. 262 (16): 7546–51. PMID 3034899.
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