Alpha,alpha-phosphotrehalase
In enzymology, an alpha,alpha-phosphotrehalase (EC 3.2.1.93) is an enzyme that catalyzes the chemical reaction
- alpha,alpha-trehalose 6-phosphate + H2O D-glucose + D-glucose 6-phosphate
| alpha,alpha-phosphotrehalase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.93 | ||||||||
| CAS number | 54576-93-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are alpha,alpha'-trehalose 6-phosphate and H2O, whereas its two products are D-glucose and D-glucose 6-phosphate.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase. This enzyme is also called phosphotrehalase. This enzyme participates in starch and sucrose metabolism.
References
- Bhumiratana A, Anderson RL, Costilow RN (1974). "Trehalose metabolism by Bacillus popilliae". J. Bacteriol. 119 (2): 484–93. PMC 245631. PMID 4369400.
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