Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase

In enzymology, a glycerol-1,2-cyclic-phosphate 2-phosphodiesterase (EC 3.1.4.42) is an enzyme that catalyzes the chemical reaction

glycerol 1,2-cyclic phosphate + H2O glycerol 1-phosphate
glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
Identifiers
EC number3.1.4.42
CAS number69458-89-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are glycerol 1,2-cyclic phosphate and H2O, whereas its product is glycerol 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase. This enzyme is also called rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase.

References

    • Clarke N, Dawson RM (1978). "rac-Glycerol 1:2-cyclic phosphate 2-phosphodiesterase, a new soluble phosphodiesterase of mammalian tissues". Biochem. J. 173 (2): 579–89. PMC 1185812. PMID 212014.


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