Ribonuclease alpha

Ribonuclease alpha (EC 3.1.26.2, 2'-O-methyl RNase) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to 5'-phosphomonoester
Ribonuclease alpha
Identifiers
EC number3.1.26.2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is specific for O-methylated RNA.

References

  1. Norton J, Roth JS (May 1967). "A ribonuclease specific for 2'-O-methylated ribonucleic acid". The Journal of Biological Chemistry. 242 (9): 2029–34. PMID 6022850.
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