Glucose-1-phosphatase

In enzymology, a glucose-1-phosphatase (EC 3.1.3.10) is an enzyme that catalyzes the chemical reaction

alpha-D-glucose 1-phosphate + H2O D-glucose + phosphate
glucose-1-phosphatase
Identifiers
EC number3.1.3.10
CAS number9001-38-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are alpha-D-glucose 1-phosphate and H2O, whereas its two products are D-glucose and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is alpha-D-glucose-1-phosphate phosphohydrolase. This enzyme participates in glycolysis and gluconeogenesis.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1NT4.

gollark: They do have completely incompatible power systems with literally everything.
gollark: One example they gave was actually itemstacks and `null` changing in meaning for them or something ridiculous like that.
gollark: ```API Update 899 4 months ago Auxiliary Update 902 13 days ago Base Update 902 13 days ago Blocks Update 902 13 days ago Containers Update 890 5 months ago Entities Update 900 3 months ago GUIs Update 902 13 days ago Items Update 902 13 days ago ModInterface Update 900 3 months ago Models Update 878 - v19a a year ago Registry Update 899 4 months ago Renders Update 901 3 months ago Resources Update 899 4 months ago Sounds Update 871 ```Wonderfully descriptive commit messages, too.
gollark: Deliberately without necessary components, so not *really*.
gollark: https://github.com/ReikaKalseki/RotaryCraft

References

    • Faulkner P (August 1955). "A hexose-1-phosphatase in silkworm blood". The Biochemical Journal. 60 (4): 590–6. PMC 1216157. PMID 13249953.
    • Turner DH, Turner JF (March 1960). "The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds". The Biochemical Journal. 74 (3): 486–91. PMC 1204246. PMID 13839934.


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