Dolichylphosphate-glucose phosphodiesterase
In enzymology, a dolichylphosphate-glucose phosphodiesterase (EC 3.1.4.48) is an enzyme that catalyzes the chemical reaction
- dolichyl beta-D-glucosyl phosphate + H2O dolichyl phosphate + D-glucose
| dolichylphosphate-glucose phosphodiesterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.4.48 | ||||||||
| CAS number | 89287-42-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are dolichyl beta-D-glucosyl phosphate and H2O, whereas its two products are dolichyl phosphate and D-glucose.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase. Other names in common use include dolichol phosphoglucose phosphodiesterase, and Dol-P-Glc phosphodiesterase. This enzyme participates in n-glycan biosynthesis.
References
- Crean EV (1984). "Synthesis and degradation of dolichyl phosphoryl glucose by the cellular slime mold, Dictyostelium discoideum". Biochim. Biophys. Acta. 792: 149–157. doi:10.1016/0005-2760(84)90216-9.
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