Mucrolysin
Mucrolysin (EC 3.4.24.54, Trimeresurus metalloendopeptidase A, mucrotoxin A) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Cleavage of Ser9-His, His10-Leu, Ala14-Leu, Leu15-Tyr and Tyr16-Leu bonds in insulin B chain
| Mucrolysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.24.54 | ||||||||
| CAS number | 85898-38-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
| Zinc metalloproteinase/disintegrin | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ? | ||||||
| UniProt | O57413 | ||||||
| |||||||
This endopeptidase from the venom of Taiwan habu snake (Protobothrops mucrosquamatus).
References
- Sugihara H, Moriura M, Nikai T (1983). "Purification and properties of a lethal, hemorrhagic protein, "mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus)". Toxicon. 21: 247–255. doi:10.1016/0041-0101(83)90009-0. PMID 6857709.
- Kishida M, Nikai T, Mori N, Kohmura S, Sugihara H (1985). "Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake)". Toxicon. 23 (4): 637–45. doi:10.1016/0041-0101(85)90368-x. PMID 3904081.
External links
- Mucrolysin at the US National Library of Medicine Medical Subject Headings (MeSH)
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