Ophiolysin
Ophiolysin (EC 3.4.24.51, Ophiophagus metalloendopeptidase) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- Cleavage of Asn3-Gln, Gln4-His, His10-Leu, Ala14-Leu, and Tyr16-Leu in insulin B chain
| Ophiolysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.24.51 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This endopeptidase is present in the venom of the king cobra (Ophiophagus hannah)
References
- Yamakawa Y, Omori-Satoh T (1988). "A protease in the venom of king cobra (Ophiophagus hannah): purification, characterization and substrate specificity on oxidized insulin B-chain". Toxicon. 26 (12): 1145–55. doi:10.1016/0041-0101(88)90299-1. PMID 3070833.
External links
- Ophiolysin at the US National Library of Medicine Medical Subject Headings (MeSH)
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