Futalosine hydrolase

Futalosine hydrolase (EC 3.2.2.26, futalosine nucleosidase, MqnB) is an enzyme with systematic name futalosine ribohydrolase.[1] This enzyme catalyses the following chemical reaction

futalosine + H2O dehypoxanthine futalosine + hypoxanthine
Futalosine hydrolase
Identifiers
EC number3.2.2.26
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme catalyses the second step of menaquinone biosynthesis.

References

  1. Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T (September 2008). "An alternative menaquinone biosynthetic pathway operating in microorganisms". Science. 321 (5896): 1670–3. doi:10.1126/science.1160446. PMID 18801996.
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