All-trans-retinyl-palmitate hydrolase

In enzymology, an all-trans-retinyl-palmitate hydrolase (EC 3.1.1.64) is an enzyme that catalyzes the chemical reaction

all-trans-retinyl palmitate + H2O all-trans-retinol + palmitate
all-trans-retinyl-palmitate hydrolase
Identifiers
EC number3.1.1.64
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are all-trans-retinyl palmitate and H2O, whereas its two products are all-trans-retinol and palmitate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is all-trans-retinyl-palmitate acylhydrolase. This enzyme participates in retinol metabolism. This enzyme has at least one effector, Detergents.

References

    • Blaner WS, Das SR, Gouras P, Flood MT (1987). "Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates of human retinal epithelial cells". J. Biol. Chem. 262 (1): 53–8. PMID 3793734.


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