Glycerophosphoinositol glycerophosphodiesterase

In enzymology, a glycerophosphoinositol glycerophosphodiesterase (EC 3.1.4.44) is an enzyme that catalyzes the chemical reaction

1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O myo-inositol + sn-glycerol 3-phosphate
glycerophosphoinositol glycerophosphodiesterase
Identifiers
EC number3.1.4.44
CAS number72414-13-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are 1-(sn-glycero-3-phospho)-1D-myo-inositol and H2O, whereas its two products are myo-inositol and sn-glycerol 3-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase. Other names in common use include sn-glycero(3)phosphoinositol glycerophosphohydrolase, and sn-glycero-3-phospho-1-inositol glycerophosphohydrolase.

References

    • Dawson RM, Hemington N, Richards DE, Irvine RF (1979). "sn-Glycero(3)phosphoinositol glycerophosphohydrolase. A new phosphodiesterase in rat tissues". Biochem. J. 182 (1): 39–49. PMC 1161232. PMID 40550.


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