Glycerophosphoinositol glycerophosphodiesterase
In enzymology, a glycerophosphoinositol glycerophosphodiesterase (EC 3.1.4.44) is an enzyme that catalyzes the chemical reaction
- 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O myo-inositol + sn-glycerol 3-phosphate
| glycerophosphoinositol glycerophosphodiesterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.4.44 | ||||||||
| CAS number | 72414-13-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 1-(sn-glycero-3-phospho)-1D-myo-inositol and H2O, whereas its two products are myo-inositol and sn-glycerol 3-phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase. Other names in common use include sn-glycero(3)phosphoinositol glycerophosphohydrolase, and sn-glycero-3-phospho-1-inositol glycerophosphohydrolase.
References
- Dawson RM, Hemington N, Richards DE, Irvine RF (1979). "sn-Glycero(3)phosphoinositol glycerophosphohydrolase. A new phosphodiesterase in rat tissues". Biochem. J. 182 (1): 39–49. PMC 1161232. PMID 40550.
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