Ag+-exporting ATPase
In enzymology, an Ag+-exporting ATPase (EC 7.2.2.15) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + Ag+in ADP + phosphate + Ag+out
| silver-exporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 7.2.2.15 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are ATP, H2O, and Ag+, whereas its 3 products are ADP, phosphate, and Ag+.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Ag+-exporting).
References
- Gupta A, Matsui K, Lo JF, Silver S (1999). "Molecular basis for resistance to silver cations in Salmonella". Nat. Med. 5 (2): 183–188. doi:10.1038/5545. PMID 9930866.
- Bury NR, Grosell M, Grover AK, Wood CM (1999). "ATP-dependent silver transport across the basolateral membrane of rainbow trout gills". Toxicol. Appl. Pharmacol. 159 (1): 1–8. doi:10.1006/taap.1999.8706. PMID 10448119.
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