Beta-diketone hydrolase
In enzymology, a beta-diketone hydrolase (EC 3.7.1.7) is an enzyme that catalyzes the chemical reaction
- nonane-4,6-dione + H2O pentan-2-one + butanoate
| beta-diketone hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.7.1.7 | ||||||||
| CAS number | 97955-12-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are nonane-4,6-dione and H2O, whereas its two products are 2-pentanone and butanoate.
This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is nonane-4,6-dione acylhydrolase. This enzyme is also called oxidized PVA hydrolase.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2J5G and 2J5S.
gollark: My phone's lock screen explains how if you find it and don't return it, demons will tear apart the threads of space and time to reach you and punish you for your crimes.
gollark: "You've alienated someone who might have helped you further. That was probably not very smart."
gollark: inb4 gnu-nobody says palaiologos is entirely right about everything always
gollark: I mean, I agree it's stupid, but that is a... <:bees:724389994663247974> way to express it.
gollark: * osmarksproject™ 1104
References
- Sakai K, Hamada N, Watanabe Y (1983). "Separation of secondary alcohol oxidase and oxidized poly(vinyl alcohol) hydrolase by hydrophobic and dye-ligand chromatographies". Agric. Biol. Chem. 47: 153–155. doi:10.1271/bbb1961.47.153.
- Sakai K, Hamada N, Watanabe Y (1985). "A new enzyme, beta-diketone hydrolase: a component of a poly(vinyl alcohol)-degrading enzyme preparation". Agric. Biol. Chem. 49 (6): 1901–1902. doi:10.1271/bbb1961.49.1901.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.