Mannitol-1-phosphatase
In enzymology, a mannitol-1-phosphatase (EC 3.1.3.22) is an enzyme that catalyzes the chemical reaction
- D-mannitol 1-phosphate + H2O D-mannitol + phosphate
| mannitol-1-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.22 | ||||||||
| CAS number | 9055-29-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are D-mannitol 1-phosphate and H2O, whereas its two products are D-mannitol and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is D-mannitol-1-phosphate phosphohydrolase. This enzyme is also called mannitol-1-phosphate phosphatase. This enzyme participates in fructose and mannose metabolism.
References
- Rumpho ME, Edwards GE, Loescher WH (1983). "A Pathway for Photosynthetic Carbon Flow to Mannitol in Celery Leaves : Activity and Localization of Key Enzymes". Plant Physiol. 73 (4): 869–873. doi:10.1104/pp.73.4.869. PMC 1066569. PMID 16663332.
- Yamada H, Okamoto K, Kodama K, Noguchi F, Tanaka S (May 1961). "Enzymatic studies on mannitol formation by Piricularia oryzae". J. Biochem. Tokyo. 49: 404–410. PMID 13787089.
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