List of enzymes
This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission [EC] numbering system. For a list of the EC numbers themselves, see:
Category:Oxidoreductases (EC 1) (Oxidoreductase)
Category:EC 1.1 (act on the CH-OH group of donors)
- Category:EC 1.1.1 (with NAD+ or NADP+ as acceptor)
- Alcohol dehydrogenase (NAD) EC 1.1.1.1
- Alcohol dehydrogenase (NADP) EC 1.1.1.2
- Homoserine dehydrogenase EC 1.1.1.3
- Aminopropanol oxidoreductase EC 1.1.1.4
- Diacetyl reductase EC 1.1.1.5
- Glycerol dehydrogenase EC 1.1.1.6
- Propanediol-phosphate dehydrogenase EC 1.1.1.7
- glycerol-3-phosphate dehydrogenase (NAD+) EC 1.1.1.8
- D-xylulose reductase EC 1.1.1.9
- L-xylulose reductase EC 1.1.1.10
- Lactate dehydrogenase EC 1.1.1.27
- Malate dehydrogenase EC 1.1.1.37
- Isocitrate dehydrogenase EC 1.1.1.42
- HMG-CoA reductase EC 1.1.1.88
- Category:EC 1.1.2 (with a cytochrome as acceptor)
- Category:EC 1.1.3 (with oxygen as acceptor)
- Category:EC 1.1.4 (with a disulfide as acceptor)
- Category:EC 1.1.5 (with a quinone or similar compound as acceptor)
- Category:EC 1.1.99 (with other acceptors)
Category:EC 1.2 (act on the aldehyde or oxo group of donors)
Category:EC 1.3 (act on the CH-CH group of donors)
- Category:EC 1.3.1 (with NAD+ or NADP+ as acceptor)
- Category:EC 1.3.2 (with a cytochrome as acceptor)
- Category:EC 1.3.3 (with oxygen as acceptor)
- Category:EC 1.3.5 (with a quinone or similar compound as acceptor)
- Category:EC 1.3.7 (with an iron-sulfur protein as acceptor)
- Category:EC 1.3.99 (with other acceptors)
Category:EC 1.4 (act on the CH-NH2 group of donors)
- Category:EC 1.4.3
Category:EC 1.5 (act on CH-NH group of donors)
- Category:EC 1.5.1 (with NAD+ or NADP+ as acceptor)
- Category:EC 1.5.3 (with oxygen as acceptor)
- Category:EC 1.5.4 (with a disulfide as acceptor)
- Category:EC 1.5.5 (with a quinone or similar compound as acceptor)
- Category:EC 1.5.7 (with an iron-sulfur protein as acceptor)
- Category:EC 1.5.8 (with a flavin as acceptor)
- Category:EC 1.5.99 (with other acceptors)
Category:EC 1.6 (act on NADH or NADPH)
- Category:EC 1.6.1 (with NAD+ or NADP+ as acceptor)
- Category:EC 1.6.2 (with a cytochrome as acceptor)
- Category:EC 1.6.3 (with oxygen as acceptor)
- Category:EC 1.6.4 now Category:EC 1.8.1
- Category:EC 1.6.5 (with a quinone or similar compound as acceptor)
- Category:EC 1.6.6 (with a nitrogenous group as acceptor)
- Category:EC 1.6.7 now Category:EC 1.18.1
- Category:EC 1.6.8 now Category:EC 1.5.1
- Category:EC 1.6.99 (with other acceptors)
Category:EC 1.7 (act on other nitrogenous compounds as donors)
- Category:EC 1.7.1 (with NAD+ or NADP+ as acceptor)
- Category:EC 1.7.2 (with a cytochrome as acceptor)
- Category:EC 1.7.3 (with oxygen as acceptor)
- Category:EC 1.7.7 (with an iron-sulfur protein as acceptor)
- Category:EC 1.7.99 (with other acceptors)
Category:EC 1.8 (act on a sulfur group of donors)
- Category:EC 1.8.1 (with NAD+ or NADP+ as acceptor)
- Category:EC 1.8.2 (with a cytochrome as acceptor)
- Category:EC 1.8.3 (with oxygen as acceptor)
- Category:EC 1.8.4 (with a disulfide as acceptor)
- Category:EC 1.8.5 (with a quinone or similar compound as acceptor)
- Category:EC 1.8.6 deleted, included in EC 2.5.1.18
- Category:EC 1.8.7 (with an iron-sulfur protein as acceptor)
- Category:EC 1.8.98 (with other, known, acceptors)
- Category:EC 1.8.99 (with other acceptors)
Category:EC 1.9 (act on a heme group of donors)
- Category:EC 1.9.3 (with oxygen as acceptor)
- Category:EC 1.9.6 (with a nitrogenous as acceptor)
- Category:EC 1.9.99 transferred, now EC 1.9.98.1
Category:EC 1.10 (act on diphenols and related substances as donors)
Category:EC 1.11 (act on peroxide as an acceptor -- peroxidases)
Category:EC 1.12 (act on hydrogen as a donor)
- Category:EC 1.12.1 (with NAD+ or NADP+ as acceptor)
- Category:EC 1.12.2 (with a cytochrome as acceptor)
- Category:EC 1.12.5 (with a quinone or similar compound as acceptor)
- Category:EC 1.12.7 (with an iron-sulfur protein as acceptor)
- Category:EC 1.12.98 (with other known acceptors)
- Category:EC 1.12.99 (with other acceptors)
Category:EC 1.13 (act on single donors with incorporation of molecular oxygen)
- Category:EC 1.13.11 (With incorporation of two atoms of oxygen)
- 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)
- Category:EC 1.13.12 (With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases))
Category:EC 1.14 (act on paired donors with incorporation of molecular oxygen)
- Cytochrome P450 oxidase
- Category:Cytochrome P450
- Category:EC 1.14.12
- Category:EC 1.14.13
- Category:EC 1.14.14
- Category:EC 1.14.16
- Category:EC 1.14.18
Category:EC 1.15 (act on superoxide radicals as acceptors)
- Category:EC 1.15.1
Category:EC 1.16 (oxidize metal ions)
- Category:EC 1.16.3
Category:EC 1.17 (act on CH or CH2 groups)
- Category:EC 1.17.1
- Category:EC 1.17.2
- Category:EC 1.17.3
- Category:EC 1.17.4
- Category:EC 1.17.5
- Category:EC 1.17.7
- Category:EC 1.17.99
Category:EC 1.18 (act on iron-sulfur proteins as donors)
- Category:EC 1.18.6
Category:EC 1.19 (act on reduced flavodoxin as donor)
- Category:EC 1.19.6
Category:EC 1.20 (act on phosphorus or arsenic as donors)
- Category:EC 1.20.1
- Category:EC 1.20.2
- Category:EC 1.20.4
- Category:EC 1.20.9
- Category:EC 1.20.99
Category:EC 1.21 (act on X-H and Y-H to form an X-Y bond)
- Category:EC 1.21.1
- Category:EC 1.21.3
- Category:EC 1.21.4
- Category:EC 1.21.99
Category:EC 1.97 (other oxidoreductases)
- Category:EC 1.97.1
Category:Transferases (EC 2) (Transferase)
Category:EC 2.1 (transfer one-carbon groups, Methylase)
Category:EC 2.3 (acyltransferases)
- Category:EC 2.3.1
- Category:EC 2.3.2
- Factor XIII EC 2.3.2.13
- Gamma glutamyl transpeptidase EC 2.3.2.2
- Transglutaminase EC 2.3.2.13
Category:EC 2.4 (glycosyltransferases)
- Category:EC 2.4.2
Category:EC 2.5
- Category:EC 2.5.1
Category:EC 2.6 (transfer nitrogenous groups)
- Category:EC 2.6.1
Category:EC 2.7 (transfer phosphorus-containing groups)
- Category:EC 2.7.2
Category:EC 2.8 (transfer sulfur-containing groups)
- EC 2.8.1.1: Thiosulfate sulfurtransferase
- EC 2.8.1.2: 3-mercaptopyruvate sulfurtransferase
- EC 2.8.1.3: Thiosulfate--thiol sulfurtransferase
- EC 2.8.1.4: tRNA uracil 4-sulfurtransferase
- EC 2.8.1.5: Thiosulfate--dithiol sulfurtransferase
- EC 2.8.1.6: Biotin synthase
- EC 2.8.1.7: Cysteine desulfurase
- EC 2.8.1.8: Lipoyl synthase
- EC 2.8.1.9: Molybdenum cofactor sulfurtransferase
- EC 2.8.1.10: Thiazole synthase
- EC 2.8.1.11: Molybdopterin synthase sulfurtransferase
- EC 2.8.1.12: Molybdopterin synthase
- EC 2.8.1.13: tRNA-uridine 2-sulfurtransferase
- EC 2.8.1.14: tRNA-5-taurinomethyluridine 2-sulfurtransferase
- EC 2.8.1.15: tRNA-5-methyluridine(54) 2-sulfurtransferase
Category:Hydrolases (EC 3) (Hydrolase)
- Hydrolytic enzyme
Category:EC 3.1 (act on ester bonds)
- Nuclease
- Endonuclease
- Exonuclease
- Category:EC 3.1.1
- Category:EC 3.1.2
- Category:EC 3.1.3
- Category:EC 3.1.4
- Phospholipase C (EC 3.1.4.3)
- CGMP specific phosphodiesterase type 5 (EC 3.1.4.17)
- Phospholipase D (EC 3.1.4.50)
- Category:EC 3.1.21
- Restriction enzyme Type 1 (EC 3.1.21.3)
- Restriction enzyme Type 2 (EC 3.1.21.4)
- Restriction enzyme Type 3 (EC 3.1.21.5)
- Restriction enzyme Type 4 (?)
- Deoxyribonuclease I (EC 3.1.21.1)
- Category:EC 3.1.26
- Category:EC 3.1.27
Category:EC 3.2 (act on sugars - glycosylases)
Category:EC 3.3 (act on ether bonds)
- Category:EC 3.3
- Adenosylmethionine hydrolase
- S-adenosyl-L-homocysteine hydrolase
- Alkenylglycerophosphocholine hydrolase
- Alkenylglycerophosphoethanolamine hydrolase
- Cholesterol-5,6-oxide hydrolase
- Hepoxilin-epoxide hydrolase
- Isochorismatase
- Leukotriene-A4 hydrolase
- Limonene-1,2-epoxide hydrolase
- Microsomal epoxide hydrolase
- Trans-epoxysuccinate hydrolase
Category:EC 3.4 (act on peptide bonds - Peptidase)
- Category:EC 3.4.11
- Category:EC 3.4.15
- Angiotensin converting enzyme
- Category:EC 3.4.21
- Serine protease
- Chymotrypsin (EC 3.4.21.1)
- Trypsin (EC 3.4.21.4)
- Thrombin (EC 3.4.21.5)
- Factor X (EC 3.4.21.6)
- Plasmin (EC 3.4.21.7)
- Acrosin (EC 3.4.21.10)
- Factor VII (EC 3.4.21.21)
- Factor IX (EC 3.4.21.22)
- Prolyl oligopeptidase (EC 3.4.21.26)
- Factor XI (EC 3.4.21.27)
- Elastase (EC 3.4.21.37)
- Factor XII (EC 3.4.21.38)
- Proteinase K (EC 3.4.21.64)
- Tissue plasminogen activator (EC 3.4.21.68)
- Protein C (EC 3.4.21.69)
- Category:EC 3.4.22
- Category:EC 3.4.23
- Category:EC 3.4.24
- Category:EC 3.4.25
Category:EC 3.5 (act on carbon-nitrogen bonds, other than peptide bonds)
- Category:EC 3.5.1 (In linear amides)
- Category:EC 3.5.2 (In cyclic amides)
- Category:EC 3.5.3 (In linear amidines)
- Category:EC 3.5.4 (In cyclic amidines)
- Category:EC 3.5.5 (In nitriles)
Category:EC 3.6 (act on acid anhydrides)
- Category:EC 3.6.1
- Category:EC 3.6.3
Category:EC 3.7 (act on carbon-carbon bonds)
Category:EC 3.8 (act on halide bonds)
- EC 3.8.1.3 Haloacetate dehalogenase
Category:EC 3.9 (act on phosphorus-nitrogen bonds)
Category:EC 3.10 (act on sulfur-nitrogen bonds)
Category:EC 3.11 (act on carbon-phosphorus bonds)
Category:EC 3.12 (act on sulfur-sulfur bonds)
Category:EC 3.13 (act on carbon-sulfur bonds)
- EC 3.13.1.1: UDP-sulfoquinovose synthase
- EC 3.13.1.3: 2'-hydroxybiphenyl-2-sulfinate desulfinase
- EC 3.13.1.4: 3-sulfinopropanoyl-CoA desulfinase
- EC 3.13.1.5: Carbon disulfide hydrolase
- EC 3.13.1.6: (CysO sulfur-carrier protein)-S-L-cysteine hydrolase
- EC 3.13.1.7: Carbonyl sulfide hydrolase
- EC 3.13.1.8: S-adenosyl-L-methionine hydrolase (adenosine-forming)
Category:Lyases (EC 4) (Lyase)
Category:EC 4.1 (carbon-carbon lyases)
- Category:EC 4.1.1
- Category:EC 4.1.2
Category:EC 4.2 (carbon-oxygen lyases)
- Category:EC 4.2.1
Category:EC 4.3 (carbon-nitrogen lyases)
- Category:EC 4.3.1
Category:EC 4.4 (carbon-sulfur lyases)
- Category:EC 4.4.1
Category:EC 4.5 (carbon-halide lyases)
- Category:EC 4.5.1
Category:Isomerases (EC 5) (Isomerase)
Category:EC 5.1 (racemases and epimerases)
- Category:EC 5.1.1
- Amino-acid racemase: Phenylalanine racemase (ATP-hydrolysing)
- Serine racemase
- Category:EC 5.1.2
- Mandelate racemase
- Category:EC 5.1.3
- UDP-glucose 4-epimerase
- Category:EC 5.1.99
- Methylmalonyl CoA epimerase
Category:EC 5.2 (cis-trans-isomerases)
- Category:EC 5.2
- FKBP: FKBP1A
- FKBP1B
- FKBP2
- FKBP3
- FKBP5
- FKBP6
- FKBP8
- FKBP9
- FKBP10
- FKBP52
- FKBPL
- Cyclophilin
- Parvulin
- Prolyl isomerase
- 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
- Beta-carotene isomerase
- Farnesol 2-isomerase
- Furylfuramide isomerase
- Linoleate isomerase
- Maleate isomerase
- Maleylacetoacetate isomerase
- Maleylpyruvate isomerase
- Parvulin
- Photoisomerase
- Prolycopene isomerase
- Prolyl isomerase
- Retinal isomerase
- Retinol isomerase
- Zeta-carotene isomerase
Category:EC 5.3 (intramolecular oxidoreductases)
- Category:EC 5.3.3
- Category:EC 5.3.4
Category:EC 5.4 (intramolecular transferases -- mutases)
- Category:EC 5.4.2
Category:EC 5.5 (intramolecular lyases)
EC number | Examples |
---|---|
EC 5.5.1.1 | Muconate cycloisomerase |
EC 5.5.1.2 | 3-carboxy-cis,cis-muconate cycloisomerase |
EC 5.5.1.3 | Tetrahydroxypteridine cycloisomerase |
EC 5.5.1.4 | Inositol-3-phosphate synthase |
EC 5.5.1.5 | Carboxy-cis,cis-muconate cyclase |
EC 5.5.1.6 | Chalcone isomerase |
EC 5.5.1.7 | Chloromuconate cycloisomerase |
EC 5.5.1.8 | (+)-bornyl diphosphate synthase |
EC 5.5.1.9 | Cycloeucalenol cycloisomerase |
EC 5.5.1.10 | Alpha-pinene-oxide decyclase |
EC 5.5.1.11 | Dichloromuconate cycloisomerase |
EC 5.5.1.12 | Copalyl diphosphate synthase |
EC 5.5.1.13 | Ent-copalyl diphosphate synthase |
EC 5.5.1.14 | Syn-copalyl-diphosphate synthase |
EC 5.5.1.15 | Terpentedienyl-diphosphate synthase |
EC 5.5.1.16 | Halimadienyl-diphosphate synthase |
EC 5.5.1.17 | (S)-beta-macrocarpene synthase |
EC 5.5.1.18 | Lycopene epsilon-cyclase |
EC 5.5.1.19 | Lycopene beta-cyclase |
EC 5.5.1.20 | Prosolanapyrone-III cycloisomerase |
EC 5.5.1.n1 | D-ribose pyranase |
EC 5.5.1.22 | Steroid Delta Isomerase |
Category:EC 5.99 (other isomerases)
- Category:EC 5.99.1
- Topoisomerase (type I: EC 5.99.1.2, type II: EC 5.99.1.3)
Category:Ligases (EC 6) (Ligase)
Category:EC 6.1 (form carbon-oxygen bonds)
Category:EC 6.2 (form carbon-sulfur bonds)
- EC 6.2.1.1: Acetate--CoA ligase
- EC 6.2.1.2: Medium-chain acyl-CoA ligase
- EC 6.2.1.3: Long-chain-fatty-acid-CoA ligase
- EC 6.2.1.4: Succinate-CoA ligase (GDP-forming)
- EC 6.2.1.5: Succinate-CoA ligase (ADP-forming)
- EC 6.2.1.6: Glutarate-CoA ligase
- EC 6.2.1.7: Cholate-CoA ligase
- EC 6.2.1.8: Oxalate-CoA ligase
- EC 6.2.1.9: Malate-CoA ligase
- EC 6.2.1.10: Acid-CoA ligase (GDP-forming)
- EC 6.2.1.11: Biotin-CoA ligase
- EC 6.2.1.12: 4-coumarate-CoA ligase
- EC 6.2.1.13: Acetate-CoA ligase (ADP-forming)
- EC 6.2.1.14: 6-carboxyhexanoate-CoA ligase
- EC 6.2.1.15: Arachidonate-CoA ligase
- EC 6.2.1.16: Acetoacetate-CoA ligase
- EC 6.2.1.17: Propionate-CoA ligase
- EC 6.2.1.18: Citrate-CoA ligase
- EC 6.2.1.19: Long-chain-fatty-acid-luciferin-component ligase
- EC 6.2.1.20: Long-chain-fatty-acid-(acyl-carrier-protein) ligase
- EC 6.2.1.21: Transferred entry: 6.2.1.30
- EC 6.2.1.22: (citrate (pro-3S)-lyase) ligase
- EC 6.2.1.23: Dicarboxylate-CoA ligase
- EC 6.2.1.24: Phytanate-CoA ligase
- EC 6.2.1.25: Benzoate-CoA ligase
- EC 6.2.1.26: o-succinylbenzoate-CoA ligase
- EC 6.2.1.27: 4-hydroxybenzoate-CoA ligase
- EC 6.2.1.28: 3a,7a-dihydroxy-5b-cholestanate-CoA ligase
- EC 6.2.1.29: Transferred entry: 6.2.1.7
- EC 6.2.1.30: Phenylacetate-CoA ligase
- EC 6.2.1.31: 2-furoate-CoA ligase
- EC 6.2.1.32: Anthranilate-CoA ligase
- EC 6.2.1.33: 4-chlorobenzoate-CoA ligase
- EC 6.2.1.34: Trans-feruloyl-CoA synthase
- EC 6.2.1.35: ACP-SH:acetate ligase
- EC 6.2.1.36: 3-hydroxypropionyl-CoA synthase
- EC 6.2.1.37: 3-hydroxybenzoate—CoA ligase
- EC 6.2.1.38: (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase
- EC 6.2.1.39: (butirosin acyl-carrier protein)—L-glutamate ligase
- EC 6.2.1.40: 4-hydroxybutyrate-CoA ligase
- EC 6.2.1.41: 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl)propanoate-CoA ligase
- EC 6.2.1.42: 3-oxocholest-4-en-26-oate-CoA ligase
- EC 6.2.1.43: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate-CoA ligase
- EC 6.2.1.44: 3-(methylthio)propionyl-CoA ligase
- EC 6.2.1.45: E1 ubiquitin-activating enzyme
- EC 6.2.1.46: L-allo-isoleucine--holo-CmaA peptidyl-carrier protein ligase
- EC 6.2.1.47: Medium-chain-fatty-acid-(acyl-carrier-protein) ligase
- EC 6.2.1.48: Carnitine-CoA ligase
- EC 6.2.1.49: Long-chain fatty acid adenylyltransferase FadD28
- EC 6.2.1.50: 4-hydroxybenzoate adenylyltransferase FadD22
- EC 6.2.1.51: 4-hydroxyphenylalkanoate adenylyltransferase FadD29
- EC 6.2.1.52: L-firefly luciferin-CoA ligase
- EC 6.2.1.53: L-proline-L-prolyl-carrier protein ligase
- EC 6.2.1.54: D-alanine-D-alanyl-carrier protein ligase
- EC 6.2.1.55: E1 SAMP-activating enzyme
Category:EC 6.3 (form carbon-nitrogen bonds)
Category:EC 6.4 (form carbon-carbon bonds)
Category:EC 6.5 (form phosphoric ester bonds)
Category:EC 6.6 (form nitrogen-metal bonds)
gollark: Some people want *genetic* children.
gollark: It [DATA LOST] so it's [REDACTED] [ERROR].
gollark: We already both have SCP-055.
gollark: In the majority of cases, at least, they are the same.
gollark: Well, the current concept of it is connected to that.
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