Snake venom factor V activator
Snake venom factor V activator (EC 3.4.21.95) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Fully activates human clotting factor V by a single cleavage at the Trp-Tyr-Leu-Arg1545-Ser-Asn-Asn-Gly bond.
| Snake venom factor V activator | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.21.95 | ||||||||
| CAS number | 471269-12-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is present in venom of Vipera russelli.
References
- Kisiel W, Canfield WM (1981). "Snake venom proteases that activate blood-coagulation factor V". Methods in Enzymology. 80 Pt C: 275–85. doi:10.1016/s0076-6879(81)80024-9. PMID 7043192.
- Tokunaga F, Nagasawa K, Tamura S, Miyata T, Iwanaga S, Kisiel W (November 1988). "The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-V alpha, -V beta, and -V gamma and their complete amino acid sequences". The Journal of Biological Chemistry. 263 (33): 17471–81. PMID 3053712.
External links
- Snake+venom+factor+V+activator at the US National Library of Medicine Medical Subject Headings (MeSH)
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