Oviductin

Oviductin (EC 3.4.21.120, oviductal protease) is an enzyme.[1][2][3] It catalyses the following chemical reaction:

Preferential cleavage at Gly-Ser-Arg373- of glycoprotein gp43 in Xenopus laevis coelemic egg envelope to yield gp41
Oviductin
Identifiers
EC number3.4.21.120
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is also found in the Japanese toad (Bufo japonicus).

References

  1. Hardy DM, Hedrick JL (May 1992). "Oviductin. Purification and properties of the oviductal protease that processes the molecular weight 43,000 glycoprotein of the Xenopus laevis egg envelope". Biochemistry. 31 (18): 4466–72. doi:10.1021/bi00133a012. PMID 1581303.
  2. Lindsay LL, Wieduwilt MJ, Hedrick JL (April 1999). "Oviductin, the Xenopus laevis oviductal protease that processes egg envelope glycoprotein gp43, increases sperm binding to envelopes, and is translated as part of an unusual mosaic protein composed of two protease and several CUB domains". Biology of Reproduction. 60 (4): 989–95. doi:10.1095/biolreprod60.4.989. PMID 10084976.
  3. Hiyoshi M, Takamune K, Mita K, Kubo H, Sugimoto Y, Katagiri C (March 2002). "Oviductin, the oviductal protease that mediates gamete interaction by affecting the vitelline coat in Bufo japonicus: its molecular cloning and analyses of expression and posttranslational activation". Developmental Biology. 243 (1): 176–84. doi:10.1006/dbio.2001.0558. PMID 11846486.
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