Phosphoenolpyruvate phosphatase

In enzymology, a phosphoenolpyruvate phosphatase (EC 3.1.3.60) is an enzyme that catalyzes the chemical reaction

phosphoenolpyruvate + H2O pyruvate + phosphate
phosphoenolpyruvate phosphatase
Identifiers
EC number3.1.3.60
CAS number122319-89-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are phosphoenolpyruvate and H2O, whereas its two products are pyruvate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is phosphoenolpyruvate phosphohydrolase. This enzyme is also called PEP phosphatase.

References

    • Duff SM, Lefebvre DD, Plaxton WC (1989). "Purification and Characterization of a Phosphoenolpyruvate Phosphatase from Brassica nigra Suspension Cells". Plant Physiol. 90 (2): 734–741. doi:10.1104/pp.90.2.734. PMC 1061789. PMID 16666836.
    • Malhotra OP; Kayastha AM (1989). "Chemical inactivation and active site groups of phosphoenolpyruvate-phosphatase from germinating mung beans (Vigna radiata)". Plant Sci. 65 (2): 161–170. doi:10.1016/0168-9452(89)90061-7.
    • Malhotra OP; Kayastha AM (1990). "Isolation and Characterization of Phosphoenolpyruvate Phosphatase from Germinating Mung Beans (Vigna radiata)". Plant Physiol. 93 (1): 194–200. doi:10.1104/pp.93.1.194. PMC 1062488. PMID 16667434.


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