Citrate lyase deacetylase

In enzymology, a citrate lyase deacetylase (EC 3.1.2.16) is an enzyme that catalyzes the chemical reaction

[citrate (pro-3S)-lyase](acetyl form) + H2O [citrate (pro-3S)-lyase](thiol form) + acetate
[citrate-(pro-3S)-lyase] thiolesterase
Identifiers
EC number3.1.2.16
CAS number58319-93-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are [[[citrate (pro-3S)-lyase](acetyl form)]] and H2O, whereas its two products are [[[citrate (pro-3S)-lyase](thiol form)]] and acetate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is [citrate-(pro-3S)-lyase](acetyl-form) hydrolase. This enzyme is also called [citrate-(pro-3S)-lyase] thiolesterase.

References

    • Giffhorn F, Rode H, Kuhn A, Gottschalk G (1980). "Citrate lyase deacetylase of Rhodopseudomonas gelatinosa. Isolation of the enzyme and studies on the inhibition by L-glutamate". Eur. J. Biochem. 111 (2): 461–71. doi:10.1111/j.1432-1033.1980.tb04961.x. PMID 7460909.


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