Exodeoxyribonuclease III
Exodeoxyribonuclease III (EC 3.1.11.2, Escherichia coli exonuclease III, E. coli exonuclease III, endoribonuclease III) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Exodeoxyribonuclease III | |||||||||
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Identifiers | |||||||||
EC number | 3.1.11.2 | ||||||||
CAS number | 9037-44-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This enzyme has a preference for double-stranded DNA.
References
- Lindahl T, Gally JA, Edelman GM (September 1969). "Properties of deoxyribonuclease 3 from mammalian tissues". The Journal of Biological Chemistry. 244 (18): 5014–9. PMID 5824576.
- Richardson CC, Kornberg A (January 1964). "A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. I. Purification of the enzyme and characterization of the phosphatase activity". The Journal of Biological Chemistry. 239: 242–50. PMID 14114850.
- Richardson CC, Lehman IR, Kornberg A (January 1964). "A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. II. Characterization of the exonuclease activity". The Journal of Biological Chemistry. 239: 251–8. PMID 14114851.
External links
- Exodeoxyribonuclease+III at the US National Library of Medicine Medical Subject Headings (MeSH)
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