Cyclomaltodextrinase

In enzymology, a cyclomaltodextrinase (EC 3.2.1.54) is an enzyme that catalyzes the chemical reaction

cyclomaltodextrin + H2O linear maltodextrin
cyclomaltodextrinase
Identifiers
EC number3.2.1.54
CAS number37288-41-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are cyclomaltodextrin and H2O, whereas its product is linear maltodextrin.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is cyclomaltodextrin dextrin-hydrolase (decyclizing). Other names in common use include cycloheptaglucanase, cyclohexaglucanase, and cyclodextrinase. This enzyme participates in starch and sucrose metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1EA9 and 1H3G.

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References

    • DePinto JA, Campbell LL (1968). "Purification and properties of the cyclodextrinase of Bacillus macerans". Biochemistry. 7 (1): 121–5. doi:10.1021/bi00841a016. PMID 4922856.


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