TRPC7

Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name.

TRPC7
Identifiers
Aliases	TRPC7, TRP7, transient receptor potential cation channel subfamily C member 7
External IDs	MGI: 1349470 HomoloGene: 22689 GeneCards: TRPC7
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.1 Start 136,213,320 bp[1] End 136,365,545 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 B1 Start 56,773,113 bp[2] End 56,895,993 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • store-operated calcium channel activity • ion channel activity • GO:0001948 protein binding • calcium channel activity • inositol 1,4,5 trisphosphate binding Cellular component • integral component of membrane • nuclear envelope • membrane • cis-Golgi network • cell membrane • integral component of plasma membrane • perinuclear region of cytoplasm • cell nucleus • cation channel complex Biological process • regulation of cytosolic calcium ion concentration • ion transport • single fertilization • platelet activation • calcium ion transmembrane transport • manganese ion transport • calcium ion transport • transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57113	26946
Ensembl	ENSG00000069018	ENSMUSG00000021541
UniProt	Q9HCX4	Q9WVC5
RefSeq (mRNA)	NM_001167576 NM_001167577 NM_020389 NM_001376901	NM_012035 NM_001302372 NM_001302373
RefSeq (protein)	NP_001161048 NP_001161049 NP_065122 NP_001363830	NP_001289301 NP_001289302 NP_036165
Location (UCSC)	Chr 5: 136.21 – 136.37 Mb	Chr 13: 56.77 – 56.9 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• TRPC

Further reading

• Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. 704. Berlin: Springer. p. 700. ISBN 978-94-007-0264-6.
• Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.
• Numaga T, Wakamori M, Mori Y (2007). "TRPC7". Handb Exp Pharmacol. 179 (179): 143–51. doi:10.1007/978-3-540-34891-7_8. PMID 17217055.

External links

• TRPC7+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

1. GRCh38: Ensembl release 89: ENSG00000069018 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021541 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.