GJB7

GJB7
Identifiers
Aliases	GJB7, CX25, bA136M9.1, connexin25, gap junction protein beta 7
External IDs	OMIM: 611921 HomoloGene: 89311 GeneCards: GJB7
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	87,329,278 bp[1]
Gene ontology
Molecular function	• gap junction channel activity;
Cellular component	• integral component of membrane; • gap junction; • cell junction; • cell membrane; • connexon; • membrane;
Biological process	• cell communication; • transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	375519
	n/a
	ENSG00000164411
	n/a
	Q6PEY0
	n/a
	NM_198568
	n/a
	NP_940970
	n/a
	Wikidata
View/Edit Human

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.[3]

Function

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[3][4]

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References

GRCh38: Ensembl release 89: ENSG00000164411 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: gap junction protein".
Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164411 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: gap junction protein".

[pmid12881038-4] Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.