KCNF1

Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene.[5][6] The protein encoded by this gene is a voltage-gated potassium channel subunit.[6]

KCNF1
Identifiers
Aliases	KCNF1, IK8, KCNF, KV5.1, kH1, potassium voltage-gated channel modifier subfamily F member 1
External IDs	OMIM: 603787 MGI: 2687399 HomoloGene: 124236 GeneCards: KCNF1
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p25.1 Start 10,911,934 bp[1] End 10,914,225 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 A1.1 Start 17,172,100 bp[2] End 17,176,888 bp[2]
Gene ontology Molecular function • ion channel activity • potassium channel activity • voltage-gated ion channel activity • voltage-gated potassium channel activity Cellular component • integral component of membrane • voltage-gated potassium channel complex • cell membrane • membrane Biological process • potassium ion transport • regulation of ion transmembrane transport • protein homooligomerization • ion transport • transmembrane transport • potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3754	382571
Ensembl	ENSG00000162975	ENSMUSG00000051726
UniProt	Q9H3M0	Q7TSH7
RefSeq (mRNA)	NM_002236	NM_201531
RefSeq (protein)	NP_002227	NP_963289
Location (UCSC)	Chr 2: 10.91 – 10.91 Mb	Chr 12: 17.17 – 17.18 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000162975 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051726 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Su K, Kyaw H, Fan P, Zeng Z, Shell BK, Carter KC, Li Y (Feb 1998). "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun. 241 (3): 675–81. doi:10.1006/bbrc.1997.7830. PMID 9434767.
6. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc. Natl. Acad. Sci. U.S.A. 99 (12): 7986–91. doi:10.1073/pnas.122617999. PMC 123007. PMID 12060745.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• Kv3.2+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
• KCNB2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)