KCNAB3

Voltage-gated potassium channel subunit beta-3 is a protein that in humans is encoded by the KCNAB3 gene.[5] The protein encoded by this gene is a voltage-gated potassium channel beta subunit.[5]

KCNAB3
Identifiers
Aliases	KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3, potassium voltage-gated channel subfamily A regulatory beta subunit 3
External IDs	OMIM: 604111 MGI: 1336208 HomoloGene: 55844 GeneCards: KCNAB3
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 7,921,859 bp[1] End 7,929,803 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B3 Start 69,326,258 bp[2] End 69,333,042 bp[2]
Gene ontology Molecular function • voltage-gated potassium channel activity • potassium channel regulator activity • voltage-gated ion channel activity Cellular component • cytoplasm • integral component of membrane • cell membrane Biological process • potassium ion transport • regulation of ion transmembrane transport • ion transport • potassium ion transmembrane transport • ion transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9196	16499
Ensembl	ENSG00000170049	ENSMUSG00000018470
UniProt	O43448	P97382
RefSeq (mRNA)	NM_004732	NM_010599
RefSeq (protein)	NP_004723	n/a
Location (UCSC)	Chr 17: 7.92 – 7.93 Mb	Chr 11: 69.33 – 69.33 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000170049 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018470 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Leicher T, Bahring R, Isbrandt D, Pongs O (Feb 1999). "Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel". J Biol Chem. 273 (52): 35095–101. doi:10.1074/jbc.273.52.35095. PMID 9857044.

Further reading

• Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• McCormack K, McCormack T, Tanouye M, et al. (1995). "Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product". FEBS Lett. 370 (1–2): 32–6. doi:10.1016/0014-5793(95)00785-8. PMID 7649300.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• KCNAB3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)