ZNF22

Zinc finger protein 22 is a protein that in humans is encoded by the ZNF22 gene.[5]

ZNF22
Identifiers
Aliases	ZNF22, HKR-T1, KOX15, ZNF422, Zfp422, zinc finger protein 22
External IDs	OMIM: 194529 MGI: 1914505 HomoloGene: 5067 GeneCards: ZNF22
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q11.21 Start 45,000,923 bp[1] End 45,005,326 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 E3 Start 116,624,016 bp[2] End 116,628,999 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • zinc ion binding • metal ion binding • DNA binding • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cell nucleus • nucleoplasm Biological process • odontogenesis • regulation of transcription, DNA-templated • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7570	67255
Ensembl	ENSG00000165512	ENSMUSG00000059878
UniProt	P17026	Q9ERU3
RefSeq (mRNA)	NM_006963	NM_026057 NM_001302439 NM_001302440
RefSeq (protein)	NP_008894 NP_008894.2	NP_001289368 NP_001289369 NP_080333
Location (UCSC)	Chr 10: 45 – 45.01 Mb	Chr 6: 116.62 – 116.63 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000165512 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059878 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZNF22 zinc finger protein 22 (KOX 15)".

Further reading

• Wu BY, Hanley EW, Turka LA, Nabel GJ (1992). "Isolation of a cDNA clone encoding a zinc finger protein highly expressed in T-leukemia lines". Blood. 80 (10): 2571–6. PMID 1421376.
• Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.
• Rousseau-Merck MF, Tunnacliffe A, Berger R, et al. (1992). "A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10". Genomics. 13 (3): 845–8. doi:10.1016/0888-7543(92)90166-P. PMID 1639412.
• Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
• Huebner K, Druck T, Croce CM, Thiesen HJ (1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am. J. Hum. Genet. 48 (4): 726–40. PMC 1682948. PMID 2014798.
• Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gao Y, Kobayashi H, Ganss B (2004). "The human KROX-26/ZNF22 gene is expressed at sites of tooth formation and maps to the locus for permanent tooth agenesis (He-Zhao deficiency)". J. Dent. Res. 82 (12): 1002–7. doi:10.1177/154405910308201213. PMID 14630903.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• ZNF22+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)