Intracellular receptor

Intracellular receptors are receptors located inside the cell rather than on its cell membrane. Classic hormones that use intracellular receptors include thyroid and steroid hormones. Examples are the class of nuclear receptors located in the cell nucleus and cytoplasm and the IP3 receptor located on the endoplasmic reticulum. The ligands that bind to them are usually intracellular second messengers like inositol trisphosphate (IP3) and extracellular lipophilic hormones like steroid hormones. Some intracrine peptide hormones also have intracellular receptors.

Examples

gollark: I believe browsers run media decoding heavily sandboxed nowadays, not that this is foolproof because ææææææææææa all computer systems are horribly broken.
gollark: But a virus and something which is detected as a virus are different.
gollark: You probably can't outside of the omnipresent media stack bugs.
gollark: X5O!P%@AP[4\PZX54(P^)7CC)7}$EICAR-STANDARD-ANTIVIRUS-TEST-FILE!$H+H* you, then.
gollark: It would be really stupid if that were possible.

See also

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