Sp4 transcription factor

Transcription factor Sp4 is a protein that in humans is encoded by the SP4 gene.[5][6]

SP4
Identifiers
AliasesSP4, HF1B, SPR-1, Sp4 transcription factor
External IDsOMIM: 600540 MGI: 107595 HomoloGene: 2341 GeneCards: SP4
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7p15.3Start21,428,043 bp[1]
End21,514,822 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6671

20688

Ensembl

ENSG00000105866

ENSMUSG00000025323

UniProt

Q02446

Q62445

RefSeq (mRNA)

NM_003112
NM_001326542
NM_001326543

NM_001166385
NM_009239

RefSeq (protein)

NP_001313471
NP_001313472
NP_003103

n/a

Location (UCSC)Chr 7: 21.43 – 21.51 MbChr 12: 118.23 – 118.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

Sp4 transcription factor has been shown to interact with E2F1.[7]

gollark: If a tiny unmeasurability error leads to a problem, just correct it at a larger scale, and we don't have that.
gollark: Well, that and "somehow influencing everything in the universe is quite hard".
gollark: I figure the main problem is "unclear/disagreed-upon definition of evil" more than anything else.
gollark: How does quantum stuff come into this?
gollark: Also, it appears so far as if personality stuff is an... emergent property, I think is the right term... of the lower-level neuron interactions, rather than emerging from quantum effects in one of the neurons or something.

References

  1. GRCh38: Ensembl release 89: ENSG00000105866 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025323 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hagen G, Müller S, Beato M, Suske G (November 1992). "Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes". Nucleic Acids Research. 20 (21): 5519–25. doi:10.1093/nar/20.21.5519. PMC 334381. PMID 1454515.
  6. "Entrez Gene: SP4 Sp4 transcription factor".
  7. Rotheneder H, Geymayer S, Haidweger E (November 1999). "Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". Journal of Molecular Biology. 293 (5): 1005–15. doi:10.1006/jmbi.1999.3213. PMID 10547281.

Further reading

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