SKF-38,393
SKF-38,393 is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist.[1] It has stimulant and anorectic effects.[2][3]
 | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| ChemSpider | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C16H17NO2 |
| Molar mass | 255.317 g·mol−1 |
| 3D model (JSmol) | |
| |
References
- Dubois A, Savasta M, Curet O, Scatton B (September 1986). "Autoradiographic distribution of the D1 agonist [3H]SKF 38393, in the rat brain and spinal cord. Comparison with the distribution of D2 dopamine receptors". Neuroscience. 19 (1): 125–37. doi:10.1016/0306-4522(86)90010-2. PMID 2946980.
- Trampus M, Ferri N, Adami M, Ongini E (April 1993). "The dopamine D1 receptor agonists, A68930 and SKF 38393, induce arousal and suppress REM sleep in the rat". European Journal of Pharmacology. 235 (1): 83–7. doi:10.1016/0014-2999(93)90823-Z. PMID 8100197.
- Cooper SJ, Francis J, Rusk IN (1990). "The anorectic effect of SK&F 38393, a selective dopamine D1 receptor agonist: a microstructural analysis of feeding and related behaviour". Psychopharmacology. 100 (2): 182–7. doi:10.1007/BF02244403. PMID 1968277.
| D1-like |
| ||||
|---|---|---|---|---|---|
| D2-like |
| ||||
| |||||
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.